Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2470626..2471283 Replicon chromosome
Accession NZ_CP120970
Organism Moellerella wisconsensis strain XJ22MSE1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag P6F44_RS10990 Protein ID WP_047255277.1
Coordinates 2470626..2471036 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag P6F44_RS10995 Protein ID WP_047255278.1
Coordinates 2471017..2471283 (-) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6F44_RS10970 2465891..2467561 - 1671 WP_277850667.1 single-stranded-DNA-specific exonuclease RecJ -
P6F44_RS10975 2467633..2468325 - 693 WP_047255274.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P6F44_RS10980 2468350..2469261 - 912 WP_047255275.1 site-specific tyrosine recombinase XerD -
P6F44_RS10985 2469482..2470000 + 519 WP_047255276.1 flavodoxin FldB -
P6F44_RS10990 2470626..2471036 - 411 WP_047255277.1 protein YgfX Toxin
P6F44_RS10995 2471017..2471283 - 267 WP_047255278.1 FAD assembly factor SdhE Antitoxin
P6F44_RS11000 2471544..2472536 + 993 WP_241500861.1 tRNA-modifying protein YgfZ -
P6F44_RS11005 2472554..2473174 + 621 WP_241500862.1 HD domain-containing protein -
P6F44_RS11010 2473346..2476225 - 2880 WP_047255281.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-133)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 137 a.a.        Molecular weight: 15525.49 Da        Isoelectric Point: 10.3270

>T275491 WP_047255277.1 NZ_CP120970:c2471036-2470626 [Moellerella wisconsensis]
VVLWKSNLSISWMAQLFSTCVHCVLGLVLLLAPWPTGNSIIWLPLLMVTIASWAKSQKNINKYKGIIVLTNGNKVQWKKN
EWSIITPPWCTRFGILLTLSALQGKPRKIKLWIAADAISEDDWRNLNQLLLQYPDI

Download         Length: 411 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10681.11 Da        Isoelectric Point: 5.1391

>AT275491 WP_047255278.1 NZ_CP120970:c2471283-2471017 [Moellerella wisconsensis]
MDIDNKARIHWACRRGMRELDISIMPFFEHEYDGLNDNEKHQFIRLLECADPDLFNWLMNHGRPDDDELYHMIKLIQQRN
KDRGPVEI

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References