Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 4035618..4036501 Replicon chromosome
Accession NZ_CP120969
Organism Pseudomonas putida strain AHSWHJXPP1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag P3X84_RS19000 Protein ID WP_060537713.1
Coordinates 4035618..4036055 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID I7C3Q7
Locus tag P3X84_RS19005 Protein ID WP_003250525.1
Coordinates 4036052..4036501 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3X84_RS18985 (P3X84_18985) 4031919..4033148 - 1230 WP_003250533.1 acyl-CoA dehydrogenase -
P3X84_RS18990 (P3X84_18990) 4033289..4034212 + 924 WP_004573723.1 LysR family transcriptional regulator -
P3X84_RS18995 (P3X84_18995) 4034406..4035560 + 1155 WP_060537721.1 aminotransferase class V-fold PLP-dependent enzyme -
P3X84_RS19000 (P3X84_19000) 4035618..4036055 - 438 WP_060537713.1 RES family NAD+ phosphorylase Toxin
P3X84_RS19005 (P3X84_19005) 4036052..4036501 - 450 WP_003250525.1 DUF2384 domain-containing protein Antitoxin
P3X84_RS19010 (P3X84_19010) 4036644..4037297 - 654 WP_004573726.1 oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB -
P3X84_RS19015 (P3X84_19015) 4037401..4038324 + 924 WP_004573727.1 LysR family transcriptional regulator -
P3X84_RS19020 (P3X84_19020) 4038373..4039203 + 831 WP_003250518.1 AraC family transcriptional regulator -
P3X84_RS19025 (P3X84_19025) 4039255..4039839 + 585 WP_060537711.1 LysE family transporter -
P3X84_RS19030 (P3X84_19030) 4039879..4041078 - 1200 WP_003250514.1 sugar transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-138)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15956.26 Da        Isoelectric Point: 5.6016

>T275490 WP_060537713.1 NZ_CP120969:c4036055-4035618 [Pseudomonas putida]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTIMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDGSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF

Download         Length: 438 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16956.46 Da        Isoelectric Point: 5.7258

>AT275490 WP_003250525.1 NZ_CP120969:c4036501-4036052 [Pseudomonas putida]
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I7C3Q7

References