Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 5850138..5850718 Replicon chromosome
Accession NZ_CP120956
Organism Delftia tsuruhatensis strain Ery-6A

Toxin (Protein)


Gene name vapC Uniprot ID A0A072T5F9
Locus tag PYR84_RS26505 Protein ID WP_016448367.1
Coordinates 5850338..5850718 (+) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A072THC0
Locus tag PYR84_RS26500 Protein ID WP_016448366.1
Coordinates 5850138..5850341 (+) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYR84_RS26490 (PYR84_26490) 5847381..5849066 - 1686 WP_277849001.1 VRR-NUC domain-containing protein -
PYR84_RS26495 (PYR84_26495) 5849175..5849987 - 813 WP_277849002.1 glucose 1-dehydrogenase -
PYR84_RS26500 (PYR84_26500) 5850138..5850341 + 204 WP_016448366.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PYR84_RS26505 (PYR84_26505) 5850338..5850718 + 381 WP_016448367.1 PIN domain-containing protein Toxin
PYR84_RS26510 (PYR84_26510) 5850796..5851548 - 753 WP_277849003.1 helix-turn-helix transcriptional regulator -
PYR84_RS26515 (PYR84_26515) 5851778..5853364 + 1587 WP_277849004.1 Ig-like domain repeat protein -
PYR84_RS26520 (PYR84_26520) 5853411..5854169 - 759 WP_016452684.1 ABC transporter permease -
PYR84_RS26525 (PYR84_26525) 5854166..5855407 - 1242 WP_016448371.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13790.24 Da        Isoelectric Point: 8.3155

>T275481 WP_016448367.1 NZ_CP120956:5850338-5850718 [Delftia tsuruhatensis]
MNPVLVDTSVWIDHFRQGNPHLAQLLQQDMALMHPLVLGELACGTPPARARTLADLQRLKPARQASMREVLALIEREQLF
GLGCGLVDITLLASALMSSGASLWSLDKRLHALAQRFGIACRSVLP

Download         Length: 381 bp

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7499.60 Da        Isoelectric Point: 4.5702

>AT275481 WP_016448366.1 NZ_CP120956:5850138-5850341 [Delftia tsuruhatensis]
MRTTVTIDDALYEEALELAEPEMDKADLFREAIKTFVRVQAAKRLAALGGSAPDMREIPRRPQGIEP

Download         Length: 204 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A072T5F9

Antitoxin

Source ID Structure
AlphaFold DB A0A072THC0

References