Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 596992..598675 Replicon chromosome
Accession NZ_CP120956
Organism Delftia tsuruhatensis strain Ery-6A

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PYR84_RS02775 Protein ID WP_277849294.1
Coordinates 596992..597846 (+) Length 285 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PYR84_RS02780 Protein ID WP_126311145.1
Coordinates 597869..598675 (+) Length 269 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYR84_RS02750 (PYR84_02750) 592844..593335 + 492 WP_016449824.1 Lrp/AsnC family transcriptional regulator -
PYR84_RS02755 (PYR84_02755) 593417..594007 + 591 WP_013804518.1 TetR/AcrR family transcriptional regulator -
PYR84_RS02760 (PYR84_02760) 594144..595028 + 885 WP_016449823.1 NAD(P)-dependent oxidoreductase -
PYR84_RS02765 (PYR84_02765) 595051..596247 + 1197 WP_277849293.1 MFS transporter -
PYR84_RS02770 (PYR84_02770) 596447..596977 + 531 WP_016449821.1 cupin domain-containing protein -
PYR84_RS02775 (PYR84_02775) 596992..597846 + 855 WP_277849294.1 alpha/beta fold hydrolase Toxin
PYR84_RS02780 (PYR84_02780) 597869..598675 + 807 WP_126311145.1 IclR family transcriptional regulator Antitoxin
PYR84_RS02785 (PYR84_02785) 598730..599527 + 798 WP_277849295.1 aspartate dehydrogenase -
PYR84_RS02790 (PYR84_02790) 599639..600400 + 762 WP_277849296.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
PYR84_RS02795 (PYR84_02795) 600413..600721 - 309 WP_016449816.1 XRE family transcriptional regulator -
PYR84_RS02800 (PYR84_02800) 600718..601065 - 348 WP_017406311.1 type II toxin-antitoxin system RelE/ParE family toxin -
PYR84_RS02810 (PYR84_02810) 602205..602480 - 276 WP_046989307.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(43-270)

Antitoxin

Transcription regulator IclR, C-terminal

(137-255)


Sequences

Toxin        


Download         Length: 285 a.a.        Molecular weight: 29690.05 Da        Isoelectric Point: 7.4024

>T275479 WP_277849294.1 NZ_CP120956:596992-597846 [Delftia tsuruhatensis]
MTAQTLQRMEQRLQAQFPEHLIALPGGAQVAWREAGDTASDFAVVMLHGISSGAASWMDVALALAPRTRVLAWDAPGYGR
STPLAPAAPTGADYARVLEQSLQALGVRRCLLVGHSLGALMGTPWAVQAGAGRVQQLVLISPAGGYGAPGMGEQQAKVRQ
GRLAALQEKGIEGLAAAIDQRLVSPAAPEPVRQWVRWNTARLHAAGYAQAVELLCGSDLGQAEGRLAMPVEVWVGEHDVV
TPPAACAAWAARLGARYVTLAAAGHASVVEQPADVAQRLATLLT

Download         Length: 855 bp

Antitoxin


Download         Length: 269 a.a.        Molecular weight: 29034.08 Da        Isoelectric Point: 5.3408

>AT275479 WP_126311145.1 NZ_CP120956:597869-598675 [Delftia tsuruhatensis]
MSDTSETLSTDNDRYTVPALERGLRLLACFTPSQPVWSAPDLARTLALPRSTVFRMLTTLEGMGYLQRSGTEYRLGLAVL
RLGYDYLSTQPLAQLAEPVLQSLCDRLGFTTNLALLDGTSVVYVARIAPAGAFQGAVRVGSRLPAHATVLGRALLQDMDA
DQLRALFGGSELPQFSESTPRSVEQLLQLLQQDHERGYAMGEGFYEPGVSSIAAPVRDAQGRIVAGLGMAVAFTEIAPGR
MADWVEQVRAAADELAGHLRTQHPGFLR

Download         Length: 807 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References