Detailed information of TA system TA275477

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 77535..78991
• Replicon: chromosome
• Accession: NZ_CP120956
• Organism: Delftia tsuruhatensis strain Ery-6A

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: PYR84_RS00345
• Protein ID: WP_277849179.1
• Coordinates: 77535..78380 (-)
• Length: 282 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: PYR84_RS00350
• Protein ID: WP_016447321.1
• Coordinates: 78377..78991 (-)
• Length: 205 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PYR84_RS00320 (PYR84_00320)	72868..74031	+	1164	WP_013799988.1	ABC transporter substrate-binding protein	-
PYR84_RS00325 (PYR84_00325)	74082..74954	+	873	WP_017405698.1	branched-chain amino acid ABC transporter permease	-
PYR84_RS00330 (PYR84_00330)	74958..76043	+	1086	WP_099732585.1	branched-chain amino acid ABC transporter permease	-
PYR84_RS00335 (PYR84_00335)	76036..76794	+	759	WP_154832998.1	ABC transporter ATP-binding protein	-
PYR84_RS00340 (PYR84_00340)	76799..77500	+	702	WP_043789493.1	ABC transporter ATP-binding protein	-
PYR84_RS00345 (PYR84_00345)	77535..78380	-	846	WP_277849179.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
PYR84_RS00350 (PYR84_00350)	78377..78991	-	615	WP_016447321.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
PYR84_RS00355 (PYR84_00355)	79099..79572	-	474	WP_012202024.1	hotdog fold thioesterase	-
PYR84_RS00360 (PYR84_00360)	79703..81217	-	1515	WP_012202025.1	acetyl-CoA hydrolase/transferase family protein	-
PYR84_RS00365 (PYR84_00365)	81425..82732	-	1308	WP_046239355.1	solute carrier family 23 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-258)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (12-57)

Sequences

Toxin

Protein

• Length: 282 a.a.
• Molecular weight: 31126.81 Da
• Isoelectric Point: 7.6892

>T275477 WP_277849179.1 NZ_CP120956:c78380-77535 [Delftia tsuruhatensis]
MSRDIAASIRARLKQCADARRQDFNLTLTYYGLERLLYRLSISPHADSYLLKGALLFAIWYEQPHRPTRDADLLGFGLDD
VDSAVSAFREICRIAVDDGIAFDAASVRGTTIRKEAGYGGVRIDLRATLDGARITLQVDIGFGDAVTPSPQAIRYPVLLD
GLPAPQLRSYPKYTVVAEKLHAICLLGMANTRMKDYFDLWVLMTEGTLDPAELRRAMAATFERRQLALPAGLPAGLSDGF
SSDAAKQAQWAAFLKKNRLEALELAPVVARLREEFQQCGIF

Nucleotide

• Length: 846 bp

Antitoxin

Protein

• Length: 205 a.a.
• Molecular weight: 21967.59 Da
• Isoelectric Point: 9.9117

>AT275477 WP_016447321.1 NZ_CP120956:c78991-78377 [Delftia tsuruhatensis]
MPAPGSALEQAVLALAEQRPLLRARDLAALGLPTMALSRLVAAGRLERVARGLYSLPGRPLSEHRSLAEVALRVPQGVVC
LLSALRVHGIGTQAPFEVWMAIPHHSPTPRIDQPALRAIRMSGAALSEGVETLQIDGVGVAVFNASKTVADCFKYRNKIG
LDVALEALRDGWAQRKLTADALWHYAAIDRVSNVMRPYLESIAA

Nucleotide

• Length: 615 bp