275436

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1393279..1394198 Replicon chromosome
Accession NZ_CP120920
Organism Bacillus paralicheniformis strain SYN-191

Toxin (Protein)


Gene name spoIISA Uniprot ID A0A6I7TYV7
Locus tag P3X35_RS07065 Protein ID WP_023856735.1
Coordinates 1393452..1394198 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID A0A6I7TM13
Locus tag P3X35_RS07060 Protein ID WP_023856734.1
Coordinates 1393279..1393452 (-) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3X35_RS07035 (P3X35_07035) 1388704..1389801 + 1098 WP_025811596.1 mannonate dehydratase -
P3X35_RS07040 (P3X35_07040) 1389777..1390625 + 849 WP_025811594.1 SDR family oxidoreductase -
P3X35_RS07045 (P3X35_07045) 1390651..1391664 + 1014 WP_079289562.1 zinc-binding alcohol dehydrogenase family protein -
P3X35_RS07050 (P3X35_07050) 1391716..1392987 + 1272 WP_025811590.1 MFS transporter -
P3X35_RS07055 (P3X35_07055) 1393054..1393185 - 132 WP_023856733.1 hypothetical protein -
P3X35_RS07060 (P3X35_07060) 1393279..1393452 - 174 WP_023856734.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
P3X35_RS07065 (P3X35_07065) 1393452..1394198 - 747 WP_023856735.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
P3X35_RS07070 (P3X35_07070) 1394308..1395306 - 999 WP_023856736.1 inorganic phosphate transporter -
P3X35_RS07075 (P3X35_07075) 1395319..1395936 - 618 WP_023856737.1 DUF47 domain-containing protein -
P3X35_RS07080 (P3X35_07080) 1396269..1398026 + 1758 WP_025811589.1 gamma-glutamyltransferase -
P3X35_RS07085 (P3X35_07085) 1398161..1398805 + 645 WP_023856740.1 YesL family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-57)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29421.87 Da        Isoelectric Point: 4.6015

>T275436 WP_023856735.1 NZ_CP120920:c1394198-1393452 [Bacillus paralicheniformis]
MLLFYQFLVWLIVLALALYVAAVWRFEKKLTEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLERKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEDGDD

Download         Length: 747 bp

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6897.99 Da        Isoelectric Point: 10.8356

>AT275436 WP_023856734.1 NZ_CP120920:c1393452-1393279 [Bacillus paralicheniformis]
MEPAFQQDHESAKKRLAFKMFKKQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA

Download         Length: 174 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6I7TYV7

Antitoxin

Source ID Structure
AlphaFold DB A0A6I7TM13

References