Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 4111361..4112560 Replicon chromosome
Accession NZ_CP120863
Organism Roseibium sp. KMA01

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag K1718_RS19020 Protein ID WP_265681196.1
Coordinates 4111922..4112560 (+) Length 213 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag K1718_RS19015 Protein ID WP_285806031.1
Coordinates 4111361..4111873 (+) Length 171 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K1718_RS18985 (K1718_18985) 4106570..4107418 - 849 WP_152502451.1 phosphonate ABC transporter, permease protein PhnE -
K1718_RS18990 (K1718_18990) 4107494..4108411 - 918 WP_152502452.1 phosphonate ABC transporter substrate-binding protein -
K1718_RS18995 (K1718_18995) 4108470..4109303 - 834 WP_152502453.1 phosphonate ABC transporter ATP-binding protein -
K1718_RS19000 (K1718_19000) 4109700..4110326 + 627 WP_265681198.1 DapH/DapD/GlmU-related protein -
K1718_RS19005 (K1718_19005) 4110519..4110842 + 324 WP_247649264.1 GFA family protein -
K1718_RS19010 (K1718_19010) 4110890..4111261 + 372 WP_152504351.1 VOC family protein -
K1718_RS19015 (K1718_19015) 4111361..4111873 + 513 WP_285806031.1 helix-turn-helix transcriptional regulator Antitoxin
K1718_RS19020 (K1718_19020) 4111922..4112560 + 639 WP_265681196.1 HD domain-containing protein Toxin
K1718_RS19025 (K1718_19025) 4112689..4113054 + 366 WP_265681195.1 STAS/SEC14 domain-containing protein -
K1718_RS19030 (K1718_19030) 4113051..4113848 - 798 WP_265681194.1 class II glutamine amidotransferase -
K1718_RS19035 (K1718_19035) 4113859..4115325 - 1467 WP_265681193.1 aminotransferase class V-fold PLP-dependent enzyme -
K1718_RS19040 (K1718_19040) 4115430..4115891 + 462 WP_152502460.1 Lrp/AsnC family transcriptional regulator -
K1718_RS19045 (K1718_19045) 4115907..4117019 - 1113 WP_265681192.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(32-162)

Antitoxin

Cro/C1-type helix-turn-helix domain

(5-43)


Sequences

Toxin        


Download         Length: 213 a.a.        Molecular weight: 24268.64 Da        Isoelectric Point: 4.8041

>T275433 WP_265681196.1 NZ_CP120863:4111922-4112560 [Roseibium sp. KMA01]
MTDQIIPADKASPLARMDADRLSGLLSFLQAAEQLKDTLRSGTTRKKRPESTAEHTWRLALMVLVFERELEGLDLQRLIK
LCLIHDLGEAISGDVPAPSQRQDDDRQERERRDFETLCAPLPKDMRDHLMALWLEYAAAETAEAQLAKAFDKLETMLQHL
LMPPGDVIFYEFNLTYGRERTDFSPLTRQIRDLVDNGTRQIMEDLQNAASRT

Download         Length: 639 bp

Antitoxin


Download         Length: 171 a.a.        Molecular weight: 19446.93 Da        Isoelectric Point: 6.9138

>AT275433 WP_285806031.1 NZ_CP120863:4111361-4111873 [Roseibium sp. KMA01]
VLNRIKQDVLAHELGVSQSRISRWESGRSHPNHKDCLRITTLLRARADSAADNALLHLVSRSSEPVHLVCDLTHRLLAMS
PAREREWRAPVSEFLHRPLWRFATDGIRSVEHRLADFGWFEPLNDDVVYWTEAADFPEMSIPESQIRISRLQLSDGSFAR
LVREESSSAA

Download         Length: 513 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References