Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2040458..2040603 Replicon chromosome
Accession NZ_CP120847
Organism Klebsiella pneumoniae strain KPHRJ

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2040494..2040596 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2040458..2040603 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5D18_RS09870 2035588..2037648 + 2061 WP_252005265.1 oligopeptidase B -
P5D18_RS09875 2037652..2038311 - 660 WP_020324964.1 exodeoxyribonuclease X -
P5D18_RS09880 2038390..2038620 - 231 WP_002911406.1 DNA polymerase III subunit theta -
P5D18_RS09885 2038733..2039107 + 375 WP_004151448.1 CopC domain-containing protein YobA -
P5D18_RS09890 2039111..2039980 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
P5D18_RS09895 2039997..2040335 + 339 WP_002911404.1 YebY family protein -
- 2040458..2040603 - 146 - - Antitoxin
- 2040494..2040596 + 103 - - Toxin
P5D18_RS09900 2040972..2041115 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
P5D18_RS09905 2041220..2042188 - 969 WP_004151446.1 VirK/YbjX family protein -
P5D18_RS09910 2042345..2042998 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
P5D18_RS09915 2042995..2043186 - 192 WP_002911395.1 YebW family protein -
P5D18_RS09920 2043284..2043523 - 240 WP_002911393.1 YebV family protein -
P5D18_RS09925 2043639..2045072 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275418 NZ_CP120847:2040494-2040596 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT275418 NZ_CP120847:c2040603-2040458 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References