Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 293396..294081 Replicon chromosome
Accession NZ_CP120732
Organism Burkholderia vietnamiensis strain LMG16232

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P4G95_RS26150 Protein ID WP_011880197.1
Coordinates 293396..293830 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P4G95_RS26155 Protein ID WP_283848963.1
Coordinates 293827..294081 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P4G95_RS26135 (P4G95_26135) 288646..289686 - 1041 WP_176295575.1 ATP-binding protein -
P4G95_RS26140 (P4G95_26140) 289680..291686 - 2007 WP_244127515.1 hypothetical protein -
P4G95_RS26145 (P4G95_26145) 291851..292858 + 1008 WP_176295576.1 serine hydrolase domain-containing protein -
P4G95_RS26150 (P4G95_26150) 293396..293830 - 435 WP_011880197.1 PIN domain-containing protein Toxin
P4G95_RS26155 (P4G95_26155) 293827..294081 - 255 WP_283848963.1 CopG family transcriptional regulator Antitoxin
P4G95_RS26160 (P4G95_26160) 294851..295063 + 213 WP_212170384.1 transposase -
P4G95_RS26165 (P4G95_26165) 295131..296921 + 1791 WP_011880194.1 nitrite/sulfite reductase -
P4G95_RS26170 (P4G95_26170) 296918..297325 + 408 WP_011880193.1 DUF934 domain-containing protein -
P4G95_RS26175 (P4G95_26175) 297340..298221 + 882 WP_283848964.1 cupin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(3-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15721.10 Da        Isoelectric Point: 7.2342

>T275384 WP_011880197.1 NZ_CP120732:c293830-293396 [Burkholderia vietnamiensis]
VITYLLDVNVLIALLDPAHVQHEPAHAWFGRVGHSAWATCPLTENGVLRIIGNPKYPNTMVSPASVAPLVVQLRSHAGHT
FWSDDVSLLDEKHVDATRLLSSAQLTDTYLLALARAHKGKLATFDRRLVVDAVPNGGKHLELIP

Download         Length: 435 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9175.34 Da        Isoelectric Point: 8.6859

>AT275384 WP_283848963.1 NZ_CP120732:c294081-293827 [Burkholderia vietnamiensis]
MSDAYKERNMRTTIDIDDDVLAFARERAKPGTSIGKVISDLARAALQRGTTNQSSRNGLPLMPVSATARPVTLDTVNQLR
DDSL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References