Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 183505..184146 Replicon chromosome
Accession NZ_CP120731
Organism Burkholderia vietnamiensis strain LMG16232

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P4G95_RS16235 Protein ID WP_011881500.1
Coordinates 183808..184146 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P4G95_RS16230 Protein ID WP_011881499.1
Coordinates 183505..183804 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P4G95_RS16205 (P4G95_16205) 178612..179883 + 1272 WP_059895582.1 anthranilate 1,2-dioxygenase large subunit AndAc -
P4G95_RS16210 (P4G95_16210) 179901..180386 + 486 WP_034194948.1 anthranilate 1,2-dioxygenase small subunit AndAd -
P4G95_RS16215 (P4G95_16215) 180413..180739 + 327 WP_011881496.1 anthranilate 1,2-dioxygenase ferredoxin subunit AndAb -
P4G95_RS16220 (P4G95_16220) 180729..181949 + 1221 WP_059462396.1 anthranilate 1,2-dioxygenase system ferredoxin--NAD(+) reductase -
P4G95_RS16225 (P4G95_16225) 182138..183424 + 1287 WP_011881498.1 DUF445 domain-containing protein -
P4G95_RS16230 (P4G95_16230) 183505..183804 - 300 WP_011881499.1 putative addiction module antidote protein Antitoxin
P4G95_RS16235 (P4G95_16235) 183808..184146 - 339 WP_011881500.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P4G95_RS16240 (P4G95_16240) 184503..186143 + 1641 WP_011881501.1 acetolactate synthase large subunit -
P4G95_RS16245 (P4G95_16245) 186172..187605 + 1434 WP_011881502.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-106)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12642.42 Da        Isoelectric Point: 9.4958

>T275383 WP_011881500.1 NZ_CP120731:c184146-183808 [Burkholderia vietnamiensis]
MVDISSNVPYSAPTYSIRTTEVFDTWFAGLQDRVARRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRA
TIWVILLCGGDKSTQQADIRAAHAMLGRLDLE

Download         Length: 339 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10548.87 Da        Isoelectric Point: 6.0633

>AT275383 WP_011881499.1 NZ_CP120731:c183804-183505 [Burkholderia vietnamiensis]
MDKISTRPWDSAAHLETDDDIADYFDACLQEGGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKARA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References