Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 300582..301411 Replicon plasmid unnamed1
Accession NZ_CP120721
Organism Vibrio coralliilyticus strain Rb102

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag P6988_RS26450 Protein ID WP_277685984.1
Coordinates 300848..301411 (+) Length 188 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag P6988_RS26445 Protein ID WP_006958592.1
Coordinates 300582..300851 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6988_RS26415 (P6988_26415) 297128..297838 + 711 WP_277685979.1 hypothetical protein -
P6988_RS26420 (P6988_26420) 298091..298492 + 402 WP_277685980.1 hypothetical protein -
P6988_RS26425 (P6988_26425) 298644..298976 + 333 WP_277685981.1 YnfA family protein -
P6988_RS26430 (P6988_26430) 299076..299573 + 498 WP_277685982.1 DUF2867 domain-containing protein -
P6988_RS26435 (P6988_26435) 299626..299733 - 108 Protein_301 transposase -
P6988_RS26440 (P6988_26440) 299934..300392 - 459 WP_277685983.1 transposase -
P6988_RS26445 (P6988_26445) 300582..300851 + 270 WP_006958592.1 DUF1778 domain-containing protein Antitoxin
P6988_RS26450 (P6988_26450) 300848..301411 + 564 WP_277685984.1 GNAT family N-acetyltransferase Toxin
P6988_RS26455 (P6988_26455) 301477..301716 - 240 WP_277685985.1 hypothetical protein -
P6988_RS26460 (P6988_26460) 302658..304751 + 2094 WP_277685986.1 TonB-dependent siderophore receptor -
P6988_RS26465 (P6988_26465) 304815..305087 + 273 WP_277685987.1 hypothetical protein -
P6988_RS26470 (P6988_26470) 305219..306187 + 969 WP_277685988.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..324189 324189


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 188 a.a.        Molecular weight: 21069.57 Da        Isoelectric Point: 9.5933

>T275379 WP_277685984.1 NZ_CP120721:300848-301411 [Vibrio coralliilyticus]
VSWGKEFVELSKSKHDRSSFDCGESELNTFIKTQAAKHMQAGISRTMVLPSSLPLLNQKYAICAFYSVAPSSISRETLPA
KLAKTLPRYPIPVFLLAQLAVHKEFHGSGLGKISLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNG
RIRMFLPMKTVEQLFSLKATNITKDDV

Download         Length: 564 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9851.36 Da        Isoelectric Point: 4.5482

>AT275379 WP_006958592.1 NZ_CP120721:300582-300851 [Vibrio coralliilyticus]
MATARLDIRLDEEIKAKAEKASALLGLRSLTEYVVRLMDEDATQVIEQHESIVVKETVFDEFMMACDKAKAPNQALLDAA
KLANESGIK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References