Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 201897..202464 Replicon plasmid unnamed1
Accession NZ_CP120721
Organism Vibrio coralliilyticus strain Rb102

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P6988_RS25935 Protein ID WP_277685932.1
Coordinates 202135..202464 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A347UR02
Locus tag P6988_RS25930 Protein ID WP_005377003.1
Coordinates 201897..202145 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6988_RS25900 (P6988_25900) 198122..198457 - 336 WP_251768734.1 helix-turn-helix transcriptional regulator -
P6988_RS25905 (P6988_25905) 199237..199716 + 480 WP_171348527.1 hypothetical protein -
P6988_RS25910 (P6988_25910) 200118..200345 - 228 Protein_196 isocitrate lyase/phosphoenolpyruvate mutase family protein -
P6988_RS25915 (P6988_25915) 200467..200913 - 447 WP_277685930.1 isoprenylcysteine carboxylmethyltransferase family protein -
P6988_RS25920 (P6988_25920) 200975..201565 - 591 WP_277685931.1 Crp/Fnr family transcriptional regulator -
P6988_RS25925 (P6988_25925) 201754..201840 - 87 WP_277686050.1 DUF3265 domain-containing protein -
P6988_RS25930 (P6988_25930) 201897..202145 + 249 WP_005377003.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
P6988_RS25935 (P6988_25935) 202135..202464 + 330 WP_277685932.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P6988_RS25940 (P6988_25940) 202938..203084 + 147 WP_277685933.1 hypothetical protein -
P6988_RS25945 (P6988_25945) 203336..203695 - 360 WP_095573461.1 hypothetical protein -
P6988_RS25950 (P6988_25950) 203894..205060 + 1167 WP_277685934.1 cyclopropane fatty acyl phospholipid synthase -
P6988_RS25955 (P6988_25955) 205550..206899 + 1350 WP_277685935.1 replicative DNA helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..324189 324189


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-74)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-75)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12788.84 Da        Isoelectric Point: 9.0154

>T275378 WP_277685932.1 NZ_CP120721:202135-202464 [Vibrio coralliilyticus]
MTYKLDFKKSALKEWKKLGSTLQQQFKKKLIERLDNPHVPASKLSGADNMYKIKLRQSGYRLVYKVEDNEIDFCLCLLLH
YVDTISIEVTPFYQVASTQHYIHTIESNC

Download         Length: 330 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9079.37 Da        Isoelectric Point: 3.9610

>AT275378 WP_005377003.1 NZ_CP120721:201897-202145 [Vibrio coralliilyticus]
MTTRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A347UR02

References