Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-yefM/YoeB-RelB
Location 2737125..2737650 Replicon chromosome
Accession NZ_CP120688
Organism Lacticaseibacillus sp. DSM 115424

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag LHUE2_RS12765 Protein ID WP_191978409.1
Coordinates 2737125..2737343 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LHUE2_RS12770 Protein ID WP_049170985.1
Coordinates 2737375..2737650 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHUE2_RS12745 (LHUE2_002549) 2734052..2734876 + 825 WP_049170991.1 LysR family transcriptional regulator -
LHUE2_RS12750 (LHUE2_002550) 2734901..2735872 - 972 WP_279306270.1 TDT family transporter -
LHUE2_RS12755 (LHUE2_002551) 2736030..2736677 - 648 WP_049170987.1 type II CAAX endopeptidase family protein -
LHUE2_RS12765 (LHUE2_002553) 2737125..2737343 - 219 WP_191978409.1 Txe/YoeB family addiction module toxin Toxin
LHUE2_RS12770 (LHUE2_002554) 2737375..2737650 - 276 WP_049170985.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LHUE2_RS12775 (LHUE2_002555) 2737817..2739418 - 1602 WP_049170983.1 ABC transporter ATP-binding protein -
LHUE2_RS12780 (LHUE2_002556) 2740507..2741151 - 645 WP_049170980.1 HD domain-containing protein -
LHUE2_RS12785 (LHUE2_002557) 2741288..2741705 + 418 Protein_2481 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-72)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8486.74 Da        Isoelectric Point: 9.0700

>T275373 WP_191978409.1 NZ_CP120688:c2737343-2737125 [Lacticaseibacillus sp. DSM 115424]
ISWFEQADKATLRKINRLITSIDRTPFDSLGKPEPLKHGLSGMWSRRITQEHRLIYEIEANTMTIISCRDHY

Download         Length: 219 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10223.54 Da        Isoelectric Point: 7.2022

>AT275373 WP_049170985.1 NZ_CP120688:c2737650-2737375 [Lacticaseibacillus sp. DSM 115424]
MDAVSYSVFRRNLKHYLQAVNDTSTPLLITSRDNEADTAVLMNKRDFDAMQETMRILSNPELMAKIRRGQAQIAAGKTRQ
HDLKDVGGGDD

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References