Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-yefM/YoeB-RelB
Location 808847..809372 Replicon chromosome
Accession NZ_CP120687
Organism Lacticaseibacillus sp. DSM 115425

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag LHUE1_RS03635 Protein ID WP_191978409.1
Coordinates 808847..809065 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LHUE1_RS03640 Protein ID WP_049170985.1
Coordinates 809097..809372 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHUE1_RS03615 (LHUE1_000723) 805774..806598 + 825 WP_049170991.1 LysR family transcriptional regulator -
LHUE1_RS03620 (LHUE1_000724) 806623..807594 - 972 WP_049170989.1 TDT family transporter -
LHUE1_RS03625 (LHUE1_000725) 807752..808399 - 648 WP_049170987.1 type II CAAX endopeptidase family protein -
LHUE1_RS03635 (LHUE1_000727) 808847..809065 - 219 WP_191978409.1 Txe/YoeB family addiction module toxin Toxin
LHUE1_RS03640 (LHUE1_000728) 809097..809372 - 276 WP_049170985.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LHUE1_RS03645 (LHUE1_000729) 809539..811140 - 1602 WP_049170983.1 ABC transporter ATP-binding protein -
LHUE1_RS03650 (LHUE1_000730) 812229..812873 - 645 WP_049170980.1 HD domain-containing protein -
LHUE1_RS03655 (LHUE1_000731) 813010..813426 + 417 WP_277848266.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-72)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8486.74 Da        Isoelectric Point: 9.0700

>T275371 WP_191978409.1 NZ_CP120687:c809065-808847 [Lacticaseibacillus sp. DSM 115425]
ISWFEQADKATLRKINRLITSIDRTPFDSLGKPEPLKHGLSGMWSRRITQEHRLIYEIEANTMTIISCRDHY

Download         Length: 219 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10223.54 Da        Isoelectric Point: 7.2022

>AT275371 WP_049170985.1 NZ_CP120687:c809372-809097 [Lacticaseibacillus sp. DSM 115425]
MDAVSYSVFRRNLKHYLQAVNDTSTPLLITSRDNEADTAVLMNKRDFDAMQETMRILSNPELMAKIRRGQAQIAAGKTRQ
HDLKDVGGGDD

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References