Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 602462..603122 Replicon chromosome
Accession NZ_CP120671
Organism Salmonella enterica strain SC2020597

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag P4B13_RS02750 Protein ID WP_000244756.1
Coordinates 602462..602875 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag P4B13_RS02755 Protein ID WP_000351186.1
Coordinates 602856..603122 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P4B13_RS02730 (598403) 598403..600136 - 1734 WP_017465473.1 single-stranded-DNA-specific exonuclease RecJ -
P4B13_RS02735 (600142) 600142..600855 - 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P4B13_RS02740 (600879) 600879..601775 - 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
P4B13_RS02745 (601888) 601888..602409 + 522 WP_001055885.1 flavodoxin FldB -
P4B13_RS02750 (602462) 602462..602875 - 414 WP_000244756.1 protein YgfX Toxin
P4B13_RS02755 (602856) 602856..603122 - 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
P4B13_RS02760 (603372) 603372..604352 + 981 WP_000874178.1 tRNA-modifying protein YgfZ -
P4B13_RS02765 (604468) 604468..605127 - 660 WP_000250289.1 hemolysin III family protein -
P4B13_RS02770 (605292) 605292..605603 - 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
P4B13_RS02775 (605762) 605762..607195 + 1434 WP_017465472.1 6-phospho-beta-glucosidase BglA -
P4B13_RS02780 (607243) 607243..607944 - 702 WP_277738631.1 transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T275331 WP_000244756.1 NZ_CP120671:c602875-602462 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT275331 WP_000351186.1 NZ_CP120671:c603122-602856 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References