Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 936219..937009 Replicon plasmid unnamed1
Accession NZ_CP120639
Organism Rhizobium sp. 32-5/1

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag P6U16_RS26185 Protein ID WP_277704300.1
Coordinates 936512..937009 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag P6U16_RS26180 Protein ID WP_277704299.1
Coordinates 936219..936515 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6U16_RS26160 (P6U16_26160) 932503..934040 + 1538 WP_277704297.1 IS3 family transposase -
P6U16_RS26165 (P6U16_26165) 934265..934393 - 129 WP_277704298.1 hypothetical protein -
P6U16_RS26170 (P6U16_26170) 934567..935284 - 718 Protein_959 YafY family protein -
P6U16_RS26175 (P6U16_26175) 935379..935989 + 611 Protein_960 glutathione S-transferase family protein -
P6U16_RS26180 (P6U16_26180) 936219..936515 + 297 WP_277704299.1 DUF1778 domain-containing protein Antitoxin
P6U16_RS26185 (P6U16_26185) 936512..937009 + 498 WP_277704300.1 GNAT family N-acetyltransferase Toxin
P6U16_RS26190 (P6U16_26190) 937770..938249 - 480 WP_277704301.1 CGNR zinc finger domain-containing protein -
P6U16_RS26195 (P6U16_26195) 938550..939482 + 933 WP_277704302.1 EamA family transporter -
P6U16_RS26200 (P6U16_26200) 939505..940197 + 693 WP_277704303.1 DUF72 domain-containing protein -
P6U16_RS26205 (P6U16_26205) 940226..940354 - 129 Protein_966 IS5/IS1182 family transposase -
P6U16_RS26210 (P6U16_26210) 940475..940819 - 345 Protein_967 transposase -
P6U16_RS26215 (P6U16_26215) 940892..941239 - 348 WP_277704304.1 IS66 family insertion sequence element accessory protein TnpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1086621 1086621


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(67-142)

Antitoxin

Vibrio phage ICP1, Orf50

(10-97)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17704.34 Da        Isoelectric Point: 6.7140

>T275323 WP_277704300.1 NZ_CP120639:936512-937009 [Rhizobium sp. 32-5/1]
VSITAPPPLADHHELAEFDSGVSELDDWLCRRARTNQVSGASRTFVVCEGSRVIAYYALASGAVKPPEAPGRLRRNMPDP
IRVAVLGRLAIDRSYQGRGIGRALVRDVGLRLLNAAEILGIRGVLVHAISDEARAFYEAVGFLPSPSDPMMLMIGLGDLN
SALAD

Download         Length: 498 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11037.65 Da        Isoelectric Point: 10.0889

>AT275323 WP_277704299.1 NZ_CP120639:936219-936515 [Rhizobium sp. 32-5/1]
MSTSHTSKSVDASVPLNMRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTIFTVSPVVYAEYLARLDAPAQ
SNERLKRTMSTKAPWDKA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References