Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 251846..252486 Replicon plasmid unnamed1
Accession NZ_CP120639
Organism Rhizobium sp. 32-5/1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P6U16_RS22725 Protein ID WP_277704580.1
Coordinates 251846..252232 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P6U16_RS22730 Protein ID WP_277704581.1
Coordinates 252232..252486 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6U16_RS22690 (P6U16_22690) 247267..247590 - 324 Protein_263 transposase -
P6U16_RS22695 (P6U16_22695) 247675..248262 - 588 WP_277704578.1 hypothetical protein -
P6U16_RS22700 (P6U16_22700) 248168..248728 - 561 WP_277704579.1 hypothetical protein -
P6U16_RS22705 (P6U16_22705) 248890..249361 - 472 Protein_266 DDE-type integrase/transposase/recombinase -
P6U16_RS22710 (P6U16_22710) 249366..249556 - 191 Protein_267 ABC transporter permease -
P6U16_RS22715 (P6U16_22715) 249562..249865 - 304 Protein_268 FtsX-like permease family protein -
P6U16_RS22720 (P6U16_22720) 249853..251126 - 1274 Protein_269 recombinase family protein -
P6U16_RS22725 (P6U16_22725) 251846..252232 - 387 WP_277704580.1 type II toxin-antitoxin system VapC family toxin Toxin
P6U16_RS22730 (P6U16_22730) 252232..252486 - 255 WP_277704581.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
P6U16_RS22735 (P6U16_22735) 252750..252863 - 114 Protein_272 IS5/IS1182 family transposase -
P6U16_RS22740 (P6U16_22740) 252905..253330 - 426 Protein_273 DDE-type integrase/transposase/recombinase -
P6U16_RS22745 (P6U16_22745) 253952..255379 + 1428 WP_277704582.1 ISNCY family transposase -
P6U16_RS22750 (P6U16_22750) 255675..257048 + 1374 WP_277704583.1 ISNCY family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1086621 1086621
- inside IScluster/Tn - - 246329..257048 10719


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14056.88 Da        Isoelectric Point: 6.2279

>T275320 WP_277704580.1 NZ_CP120639:c252232-251846 [Rhizobium sp. 32-5/1]
MVIDTSAIVAIFFNEPDAANYRERIANDPIRFISAATLVEASMVIEGRFGEAGGAELDLWVHKANVEVVAVTAEHADQAR
RAWRRYGKGRHPASLNYGDCFSYALATLAGEPLLFKGNDFKQTNIRAA

Download         Length: 387 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9369.78 Da        Isoelectric Point: 5.1599

>AT275320 WP_277704581.1 NZ_CP120639:c252486-252232 [Rhizobium sp. 32-5/1]
MALSIKDPETEKLARALAARTGETITIATRRALEERLKRMGSNAKKDALMQDMEAMQRRLIALPILDDRSADDIIGYDEN
GLPN

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References