Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5134731..5135259 Replicon chromosome
Accession NZ_CP120626
Organism Pseudomonas sp. NyZ480

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P3R38_RS23615 Protein ID WP_023382869.1
Coordinates 5134731..5135030 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2L1HF13
Locus tag P3R38_RS23620 Protein ID WP_023382870.1
Coordinates 5135020..5135259 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3R38_RS23580 (P3R38_23580) 5129861..5130550 + 690 WP_023382809.1 ABC transporter permease -
P3R38_RS23585 (P3R38_23585) 5130623..5131828 + 1206 WP_277686659.1 methyltransferase -
P3R38_RS23590 (P3R38_23590) 5132156..5132428 - 273 WP_023382811.1 DUF3077 domain-containing protein -
P3R38_RS23595 (P3R38_23595) 5132434..5132700 - 267 WP_277686660.1 hypothetical protein -
P3R38_RS23600 (P3R38_23600) 5133222..5133470 + 249 WP_023382813.1 hypothetical protein -
P3R38_RS23615 (P3R38_23615) 5134731..5135030 - 300 WP_023382869.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P3R38_RS23620 (P3R38_23620) 5135020..5135259 - 240 WP_023382870.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
P3R38_RS23625 (P3R38_23625) 5135599..5137878 - 2280 WP_104882327.1 TonB-dependent siderophore receptor -
P3R38_RS23630 (P3R38_23630) 5138035..5138754 + 720 WP_277686662.1 response regulator transcription factor -
P3R38_RS23635 (P3R38_23635) 5138747..5140123 + 1377 WP_023382873.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 5133753..5134193 440


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-70)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11496.39 Da        Isoelectric Point: 10.2270

>T275285 WP_023382869.1 NZ_CP120626:c5135030-5134731 [Pseudomonas sp. NyZ480]
MTYSLEFDARALKEWQKLGDTVRQQLKKKLASVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIEQEVVVFVVAVDK
REREQAYLKAAERVVGKTS

Download         Length: 300 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9122.53 Da        Isoelectric Point: 4.6182

>AT275285 WP_023382870.1 NZ_CP120626:c5135259-5135020 [Pseudomonas sp. NyZ480]
MASINVRIDDDLKIRAYRELERLGVTPSELMRQALQYVAERGQLPFKPVLMTDEDEALLAIVRERLADPQRVRVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2L1HF13

References