275272

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yxiD-yxxD/-
Location 3590402..3591456 Replicon chromosome
Accession NZ_CP120618
Organism Priestia megaterium strain DSM 1804

Toxin (Protein)


Gene name yxiD Uniprot ID D5DPQ4
Locus tag P5632_RS19760 Protein ID WP_013056650.1
Coordinates 3590833..3591456 (-) Length 208 a.a.

Antitoxin (Protein)


Gene name yxxD Uniprot ID D5DPQ5
Locus tag P5632_RS19755 Protein ID WP_013056651.1
Coordinates 3590402..3590830 (-) Length 143 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5632_RS19740 (P5632_19745) 3585480..3586397 - 918 WP_049787036.1 hypothetical protein -
P5632_RS19745 (P5632_19750) 3586390..3588255 - 1866 WP_013056653.1 AAA family ATPase -
P5632_RS19750 (P5632_19755) 3588733..3589884 - 1152 WP_013056652.1 suppressor of fused domain protein -
P5632_RS19755 (P5632_19760) 3590402..3590830 - 429 WP_013056651.1 SMI1/KNR4 family protein Antitoxin
P5632_RS19760 (P5632_19765) 3590833..3591456 - 624 WP_013056650.1 hypothetical protein Toxin
P5632_RS19765 (P5632_19770) 3591725..3593881 - 2157 WP_013056649.1 type IA DNA topoisomerase -
P5632_RS19770 (P5632_19775) 3593998..3594846 - 849 WP_162485295.1 GIY-YIG nuclease family protein -
P5632_RS19775 (P5632_19780) 3595418..3595681 + 264 WP_013056647.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 208 a.a.        Molecular weight: 24250.27 Da        Isoelectric Point: 9.4113

>T275272 WP_013056650.1 NZ_CP120618:c3591456-3590833 [Priestia megaterium]
MQFISDIEIWYDKDAKRYRNKETGQFTRGPNLVHEAGSGNVQPLEVPVVESVTVNKQNDSMKGTSVFDPDLVKAYLKDVE
SKTRLKVHKIQVEFLKESLRNNKFEKLTPKETAKHRGRFTTSLKNKLIEEWEEKTNQKWPRYTEEVYDQSGEIARHIGQP
YDAHHLIENNFSGPHEWWNIHPAKYPDEHQQGIHGKGAPSRMLFPRR

Download         Length: 624 bp

Antitoxin


Download         Length: 143 a.a.        Molecular weight: 16623.64 Da        Isoelectric Point: 3.9139

>AT275272 WP_013056651.1 NZ_CP120618:c3590830-3590402 [Priestia megaterium]
MADFKFINNGENKIYNLSEEEILKAEDRMGIRFPDDLRQLYLEVGYGFIKEPSNNAINRIMGPGTVANVKLREGVFEFDP
DLDELDEEDKLIFFEVNEGIYISLDLKLPNNPVFYFDTQIADSLEDFLKKFINDNEYYIDLE

Download         Length: 429 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W3N964

Antitoxin

Source ID Structure
AlphaFold DB A0A7W3N954

References