Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4839898..4840395 | Replicon | chromosome |
Accession | NZ_CP120567 | ||
Organism | Escherichia coli strain A0 34/86 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | P5707_RS23510 | Protein ID | WP_001173343.1 |
Coordinates | 4839898..4840071 (-) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | S1NQ59 |
Locus tag | P5707_RS23515 | Protein ID | WP_001312331.1 |
Coordinates | 4840099..4840395 (-) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
P5707_RS23500 (4836568) | 4836568..4838025 | + | 1458 | WP_000856826.1 | dipeptide/tripeptide permease DtpC | - |
P5707_RS23505 (4838262) | 4838262..4839779 | + | 1518 | WP_000003805.1 | lysine--tRNA ligase | - |
P5707_RS23510 (4839898) | 4839898..4840071 | - | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
P5707_RS23515 (4840099) | 4840099..4840395 | - | 297 | WP_001312331.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
P5707_RS23520 (4840624) | 4840624..4840896 | - | 273 | WP_000405647.1 | GNAT family N-acetyltransferase | - |
P5707_RS23525 (4840908) | 4840908..4841138 | - | 231 | WP_001683478.1 | 4Fe-4S mono-cluster protein YjdI | - |
P5707_RS23530 (4841319) | 4841319..4842950 | + | 1632 | WP_001216466.1 | sensor histidine kinase | - |
P5707_RS23535 (4842947) | 4842947..4843666 | + | 720 | WP_000611291.1 | two-component system response regulator DcuR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | S1NQ59 |