275186

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1501881..1502539 Replicon chromosome
Accession NZ_CP120567
Organism Escherichia coli strain A0 34/86

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag P5707_RS07165 Protein ID WP_021520983.1
Coordinates 1501881..1502201 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag P5707_RS07170 Protein ID WP_021520982.1
Coordinates 1502222..1502539 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5707_RS07150 (1497303) 1497303..1498751 - 1449 WP_000772886.1 NADP-dependent succinate-semialdehyde dehydrogenase -
P5707_RS07155 (1498774) 1498774..1500042 - 1269 WP_000271981.1 L-2-hydroxyglutarate oxidase -
P5707_RS07160 (1500062) 1500062..1501039 - 978 WP_021520984.1 glutarate dioxygenase GlaH -
P5707_RS07165 (1501881) 1501881..1502201 - 321 WP_021520983.1 TA system toxin CbtA family protein Toxin
P5707_RS07170 (1502222) 1502222..1502539 - 318 WP_021520982.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
P5707_RS07175 (1502558) 1502558..1502779 - 222 WP_021520981.1 DUF987 domain-containing protein -
P5707_RS07180 (1502788) 1502788..1503264 - 477 WP_021520980.1 RadC family protein -
P5707_RS07185 (1503280) 1503280..1503738 - 459 WP_021520979.1 antirestriction protein -
P5707_RS07190 (1503834) 1503834..1504073 - 240 WP_021520978.1 DUF905 domain-containing protein -
P5707_RS07195 (1504173) 1504173..1505081 - 909 WP_021520977.1 Ivy family c-type lysozyme inhibitor -
P5707_RS07200 (1505150) 1505150..1505317 - 168 Protein_1398 DUF4339 domain-containing protein -
P5707_RS07205 (1505355) 1505355..1506050 - 696 WP_021520976.1 hypothetical protein -
P5707_RS07210 (1506277) 1506277..1507104 - 828 WP_021520975.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-104)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12162.18 Da        Isoelectric Point: 7.1656

>T275186 WP_021520983.1 NZ_CP120567:c1502201-1501881 [Escherichia coli]
MKTLPATTLWAAKPCLSPVIVWQMLLSRLLDQHYGLTLNDTPFSDETVIKEHIDAGISLADAVNFLVEKYELVRIDRKGF
SWQEQSPFITAVDILKARRAMREMRT

Download         Length: 321 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11997.54 Da        Isoelectric Point: 6.3142

>AT275186 WP_021520982.1 NZ_CP120567:c1502539-1502222 [Escherichia coli]
MSNITWGLQRDITPRLGARLVQEGNQLHYLADRASITGKFSDVECRKLDETFPHFISQMESMLTTDELNPRHAHCVTLYH
NGFTCEADTLGSCGYIYITVYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References