Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2191342..2191610 Replicon chromosome
Accession NZ_CP120563
Organism Escherichia coli strain H22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2191470..2191572 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2191342..2191610 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5708_RS10595 2187896..2188558 - 663 WP_000944256.1 exodeoxyribonuclease X -
P5708_RS10600 2188581..2189237 - 657 WP_277706598.1 carbon-nitrogen hydrolase family protein YobB -
P5708_RS10605 2189339..2189569 - 231 WP_000916763.1 DNA polymerase III subunit theta -
P5708_RS10610 2189708..2190082 + 375 WP_000168747.1 CopC domain-containing protein YobA -
P5708_RS10615 2190086..2190958 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
P5708_RS10620 2190971..2191312 + 342 WP_000976472.1 YebY family protein -
- 2191342..2191610 - 269 - - Antitoxin
- 2191470..2191572 + 103 - - Toxin
P5708_RS10625 2191707..2192363 + 657 WP_001357783.1 protein-serine/threonine phosphatase -
P5708_RS10630 2192364..2192555 - 192 WP_001317886.1 YebW family protein -
P5708_RS10635 2192660..2192896 - 237 WP_001295499.1 YebV family protein -
P5708_RS10640 2193014..2194453 - 1440 WP_201478593.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275160 NZ_CP120563:2191470-2191572 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT275160 NZ_CP120563:c2191610-2191342 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References