Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2253558..2253826 Replicon chromosome
Accession NZ_CP120549
Organism Escherichia coli strain B1172

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2253686..2253788 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2253558..2253826 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5710_RS10575 2250112..2250774 - 663 WP_000944256.1 exodeoxyribonuclease X -
P5710_RS10580 2250797..2251453 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
P5710_RS10585 2251555..2251785 - 231 WP_000916763.1 DNA polymerase III subunit theta -
P5710_RS10590 2251924..2252298 + 375 WP_000168747.1 CopC domain-containing protein YobA -
P5710_RS10595 2252302..2253174 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
P5710_RS10600 2253187..2253528 + 342 WP_000976472.1 YebY family protein -
- 2253558..2253826 - 269 - - Antitoxin
- 2253686..2253788 + 103 - - Toxin
P5710_RS10605 2253923..2254579 + 657 WP_000812742.1 protein-serine/threonine phosphatase -
P5710_RS10610 2254580..2254771 - 192 WP_001317886.1 YebW family protein -
P5710_RS10615 2254876..2255112 - 237 WP_001295499.1 YebV family protein -
P5710_RS10620 2255230..2256669 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275102 NZ_CP120549:2253686-2253788 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT275102 NZ_CP120549:c2253826-2253558 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References