Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3879755..3880412 Replicon chromosome
Accession NZ_CP120524
Organism Enterobacter roggenkampii strain 0-E

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag P3S52_RS19840 Protein ID WP_032653292.1
Coordinates 3879755..3880165 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W7NX65
Locus tag P3S52_RS19845 Protein ID WP_006178375.1
Coordinates 3880146..3880412 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3S52_RS19820 (P3S52_19840) 3875748..3877481 - 1734 WP_032653290.1 single-stranded-DNA-specific exonuclease RecJ -
P3S52_RS19825 (P3S52_19845) 3877487..3878200 - 714 WP_008499708.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P3S52_RS19830 (P3S52_19850) 3878229..3879125 - 897 WP_008499709.1 site-specific tyrosine recombinase XerD -
P3S52_RS19835 (P3S52_19855) 3879227..3879748 + 522 WP_023309099.1 flavodoxin FldB -
P3S52_RS19840 (P3S52_19860) 3879755..3880165 - 411 WP_032653292.1 protein YgfX Toxin
P3S52_RS19845 (P3S52_19865) 3880146..3880412 - 267 WP_006178375.1 FAD assembly factor SdhE Antitoxin
P3S52_RS19850 (P3S52_19870) 3880707..3881687 + 981 WP_032653295.1 tRNA-modifying protein YgfZ -
P3S52_RS19855 (P3S52_19875) 3881772..3882431 - 660 WP_032653297.1 hemolysin III family protein -
P3S52_RS19860 (P3S52_19880) 3882697..3883428 + 732 WP_021242053.1 MurR/RpiR family transcriptional regulator -
P3S52_RS19865 (P3S52_19885) 3883545..3884978 + 1434 WP_023294510.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16069.03 Da        Isoelectric Point: 10.9468

>T275094 WP_032653292.1 NZ_CP120524:c3880165-3879755 [Enterobacter roggenkampii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKADGGRCQHLWLAADSMDAAEWRDLRRMLLQQTTQG

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.05 Da        Isoelectric Point: 5.1340

>AT275094 WP_006178375.1 NZ_CP120524:c3880412-3880146 [Enterobacter roggenkampii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB W7NX65

References