Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 2603146..2603669 Replicon chromosome
Accession NZ_CP120508
Organism Paraburkholderia sp. SUR17

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag P2869_RS11355 Protein ID WP_042303647.1
Coordinates 2603146..2603412 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P2869_RS11360 Protein ID WP_042303648.1
Coordinates 2603409..2603669 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2869_RS11335 (P2869_11335) 2598300..2599811 - 1512 WP_277596512.1 FGGY-family carbohydrate kinase -
P2869_RS11340 (P2869_11340) 2600026..2601768 + 1743 WP_277596513.1 glycerol-3-phosphate dehydrogenase/oxidase -
P2869_RS11345 (P2869_11345) 2601765..2602547 + 783 WP_277596514.1 GntR family transcriptional regulator -
P2869_RS11350 (P2869_11350) 2602590..2602955 + 366 Protein_2237 IS5/IS1182 family transposase -
P2869_RS11355 (P2869_11355) 2603146..2603412 - 267 WP_042303647.1 Txe/YoeB family addiction module toxin Toxin
P2869_RS11360 (P2869_11360) 2603409..2603669 - 261 WP_042303648.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
P2869_RS11365 (P2869_11365) 2604439..2604705 + 267 WP_277598120.1 hypothetical protein -
P2869_RS11370 (P2869_11370) 2604876..2607446 - 2571 WP_277596515.1 DUF2309 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2603146..2616836 13690


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10461.86 Da        Isoelectric Point: 7.9846

>T275082 WP_042303647.1 NZ_CP120508:c2603412-2603146 [Paraburkholderia sp. SUR17]
MSGALNIMWTAEAWDDYVYWQGQDKRTLKRINQLIKDMQRSPFEGIGKPESLKENLTGFWSRRIDETNRLVYEVASTQIN
IVSCRYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9708.07 Da        Isoelectric Point: 7.3196

>AT275082 WP_042303648.1 NZ_CP120508:c2603669-2603409 [Paraburkholderia sp. SUR17]
MRTIPFTDARANLKRVIDQVVDDVDVTLITRRDAPNAVVMSQEHYDSLMETVHLLRSPANVAHLERSIAQSRAGKVKPRK
LVDDSE

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References