Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2733975..2734118 Replicon chromosome
Accession NZ_CP120397
Organism Salmonella enterica subsp. enterica serovar Typhi strain 1521-2017_CI

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2733977..2734079 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2733975..2734118 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVA76_RS13605 (PVA76_13605) 2731253..2732383 + 1131 WP_000529513.1 GGDEF domain-containing protein -
PVA76_RS13610 (PVA76_13610) 2732669..2733064 - 396 Protein_2664 DUF977 family protein -
PVA76_RS13615 (PVA76_13615) 2733077..2733187 - 111 Protein_2665 replication protein -
PVA76_RS13620 (PVA76_13620) 2733188..2733549 + 362 Protein_2666 recombinase RecT -
PVA76_RS13625 (PVA76_13625) 2733548..2733856 + 309 Protein_2667 tyrosine-type recombinase/integrase -
- 2733975..2734118 + 144 - - Antitoxin
- 2733977..2734079 - 103 - - Toxin
PVA76_RS13630 (PVA76_13630) 2734220..2734573 - 354 WP_000722366.1 YebY family protein -
PVA76_RS13635 (PVA76_13635) 2734590..2735465 - 876 WP_000979693.1 copper homeostasis membrane protein CopD -
PVA76_RS13640 (PVA76_13640) 2735466..2735840 - 375 WP_001681742.1 CopC domain-containing protein YobA -
PVA76_RS13645 (PVA76_13645) 2735978..2736208 + 231 WP_000856224.1 DNA polymerase III subunit theta -
PVA76_RS13650 (PVA76_13650) 2736316..2736972 + 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
PVA76_RS13655 (PVA76_13655) 2736996..2737694 + 699 WP_000944282.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2710437..2755991 45554


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275026 NZ_CP120397:c2734079-2733977 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT275026 NZ_CP120397:2733975-2734118 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References