Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2773879..2774022 Replicon chromosome
Accession NZ_CP120395
Organism Salmonella enterica subsp. enterica serovar Typhi strain 1698-2017_CI

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2773881..2773983 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2773879..2774022 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVA70_RS13945 (PVA70_13945) 2771157..2772287 + 1131 WP_000529513.1 GGDEF domain-containing protein -
PVA70_RS13950 (PVA70_13950) 2772573..2772968 - 396 Protein_2734 DUF977 family protein -
PVA70_RS13955 (PVA70_13955) 2772981..2773091 - 111 Protein_2735 replication protein -
PVA70_RS13960 (PVA70_13960) 2773092..2773453 + 362 Protein_2736 recombinase RecT -
PVA70_RS13965 (PVA70_13965) 2773452..2773760 + 309 Protein_2737 tyrosine-type recombinase/integrase -
- 2773879..2774022 + 144 - - Antitoxin
- 2773881..2773983 - 103 - - Toxin
PVA70_RS13970 (PVA70_13970) 2774124..2774477 - 354 WP_000722366.1 YebY family protein -
PVA70_RS13975 (PVA70_13975) 2774494..2775369 - 876 WP_000979693.1 copper homeostasis membrane protein CopD -
PVA70_RS13980 (PVA70_13980) 2775370..2775744 - 375 WP_001681742.1 CopC domain-containing protein YobA -
PVA70_RS13985 (PVA70_13985) 2775882..2776112 + 231 WP_000856224.1 DNA polymerase III subunit theta -
PVA70_RS13990 (PVA70_13990) 2776220..2776876 + 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
PVA70_RS13995 (PVA70_13995) 2776900..2777598 + 699 WP_000944282.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2750340..2795895 45555


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T274993 NZ_CP120395:c2773983-2773881 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT274993 NZ_CP120395:2773879-2774022 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References