274942

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1009395..1009988 Replicon chromosome
Accession NZ_CP120377
Organism Pseudomonas sp. G11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P2T68_RS04480 Protein ID WP_102625774.1
Coordinates 1009686..1009988 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A855JY32
Locus tag P2T68_RS04475 Protein ID WP_024073150.1
Coordinates 1009395..1009682 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2T68_RS04455 (P2T68_04455) 1005798..1007867 - 2070 WP_024073146.1 TonB-dependent copper receptor -
P2T68_RS04460 (P2T68_04460) 1007960..1008361 - 402 WP_024073147.1 DUF2946 domain-containing protein -
P2T68_RS04465 (P2T68_04465) 1008372..1008854 - 483 WP_168232253.1 copper chaperone PCu(A)C -
P2T68_RS04470 (P2T68_04470) 1008902..1009297 - 396 WP_102625775.1 DUF2946 domain-containing protein -
P2T68_RS04475 (P2T68_04475) 1009395..1009682 - 288 WP_024073150.1 putative addiction module antidote protein Antitoxin
P2T68_RS04480 (P2T68_04480) 1009686..1009988 - 303 WP_102625774.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P2T68_RS04485 (P2T68_04485) 1010506..1010760 + 255 WP_024073152.1 DUF6124 family protein -
P2T68_RS04490 (P2T68_04490) 1010804..1011127 - 324 WP_024073153.1 transcriptional regulator -
P2T68_RS04495 (P2T68_04495) 1011133..1011465 - 333 WP_024073154.1 addiction module protein -
P2T68_RS04500 (P2T68_04500) 1011522..1012247 - 726 WP_024073155.1 cobalt-precorrin-6A reductase -
P2T68_RS04505 (P2T68_04505) 1012244..1013449 - 1206 WP_277379096.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
P2T68_RS04510 (P2T68_04510) 1013545..1014834 + 1290 WP_227496844.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-91)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11775.50 Da        Isoelectric Point: 10.0002

>T274942 WP_102625774.1 NZ_CP120377:c1009988-1009686 [Pseudomonas sp. G11]
MIQFKKSKHFLEWLDSLRSKPARARVLARLDHAQWGNFGDCEALGNGVFEMRIHYGPGYRVYFTRRDEVVYLLLIGGDKS
TQKRDIQRAKQIAEDFEKKE

Download         Length: 303 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10391.78 Da        Isoelectric Point: 4.4791

>AT274942 WP_024073150.1 NZ_CP120377:c1009682-1009395 [Pseudomonas sp. G11]
MNEFTDFDVAEHLKNPEDMAEYLEACFEEDTGDGLLIRSALNNIARAQGMTQVARDAGLGRESLYKALSSNGNPEFATIM
KVMKALGLKLHATAI

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A855JY32

References