Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 2598665..2599376 Replicon chromosome
Accession NZ_CP120376
Organism Pseudomonas nitroreducens strain L4

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag P3T65_RS12045 Protein ID WP_226046080.1
Coordinates 2598665..2599099 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag P3T65_RS12050 Protein ID WP_226046081.1
Coordinates 2599104..2599376 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3T65_RS12040 (P3T65_12040) 2596585..2598627 + 2043 WP_277369311.1 exodeoxyribonuclease V subunit alpha -
P3T65_RS12045 (P3T65_12045) 2598665..2599099 - 435 WP_226046080.1 type II toxin-antitoxin system VapC family toxin Toxin
P3T65_RS12050 (P3T65_12050) 2599104..2599376 - 273 WP_226046081.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
P3T65_RS12055 (P3T65_12055) 2599510..2602356 + 2847 WP_065086150.1 ATP-binding protein -
P3T65_RS12060 (P3T65_12060) 2602335..2603531 + 1197 WP_024767535.1 EAL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-131)

Antitoxin

SpoVT-AbrB domain

(17-53)


Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15552.78 Da        Isoelectric Point: 4.8185

>T274938 WP_226046080.1 NZ_CP120376:c2599099-2598665 [Pseudomonas nitroreducens]
VATPVTYMLDTNICSFIMRQNPPQVLQRLQKAAESGNRLVISAITHAELRYGAASPKAPKAVAAWIDALVQRLDDVLPWD
IDAVDSSAKLMSLLLDSGTPIGPNDTGIASHALATDCVIVTNNTREFRRVPGLVVEDWCNSEPA

Download         Length: 435 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9917.17 Da        Isoelectric Point: 4.2342

>AT274938 WP_226046081.1 NZ_CP120376:c2599376-2599104 [Pseudomonas nitroreducens]
MLSDLEAPTPTTTVSLFRNGKNQAVRIPRDMEFKGVTELVMTREGDTLILRPSRPTWSSLAELEPVDADFLGDRPDVIAP
SRLGFGDDEG

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References