Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 116435..116970 Replicon chromosome
Accession NZ_CP120376
Organism Pseudomonas nitroreducens strain L4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag P3T65_RS00590 Protein ID WP_277368886.1
Coordinates 116695..116970 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0F0DTW6
Locus tag P3T65_RS00585 Protein ID WP_024762620.1
Coordinates 116435..116704 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3T65_RS00560 (P3T65_00560) 111613..112740 - 1128 WP_277368885.1 GGDEF domain-containing protein -
P3T65_RS00565 (P3T65_00565) 112993..114516 + 1524 WP_024762623.1 fumarate hydratase -
P3T65_RS00570 (P3T65_00570) 114648..114950 - 303 WP_017519692.1 ribbon-helix-helix domain-containing protein -
P3T65_RS00575 (P3T65_00575) 114984..115565 - 582 WP_065084442.1 DJ-1/PfpI family protein -
P3T65_RS00580 (P3T65_00580) 115669..116247 - 579 WP_024762621.1 DUF2846 domain-containing protein -
P3T65_RS00585 (P3T65_00585) 116435..116704 + 270 WP_024762620.1 ribbon-helix-helix protein, CopG family Antitoxin
P3T65_RS00590 (P3T65_00590) 116695..116970 + 276 WP_277368886.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P3T65_RS00595 (P3T65_00595) 116990..117577 - 588 WP_065084471.1 GNAT family acetyltransferase -
P3T65_RS00600 (P3T65_00600) 117761..118999 - 1239 WP_205896507.1 acyltransferase -
P3T65_RS00605 (P3T65_00605) 119088..120245 - 1158 WP_024762616.1 phospholipase D-like domain-containing protein -
P3T65_RS00610 (P3T65_00610) 120242..120817 - 576 WP_024762615.1 YceI family protein -
P3T65_RS00615 (P3T65_00615) 120929..121834 - 906 WP_170859783.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10493.07 Da        Isoelectric Point: 9.6182

>T274936 WP_277368886.1 NZ_CP120376:116695-116970 [Pseudomonas nitroreducens]
MRVIYAPAALRDLDRLRRFLRETNPTAARRAGQIILQATQALGAYPQMGRLIDDLPIEFREWPIDFGDSGYLARYHIDGE
TLVTLAIRHQR

Download         Length: 276 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10472.62 Da        Isoelectric Point: 4.4422

>AT274936 WP_024762620.1 NZ_CP120376:116435-116704 [Pseudomonas nitroreducens]
MATSVKLDEEMLARVRELAELRQRSPHWIMREAIGQYVVREEQREKLKRDTEQAWEEFQATGQHVTAEAVESWLNSWGDE
DEQAAPKCE

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0F0DTW6

References