Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1765524..1766059 Replicon chromosome
Accession NZ_CP120374
Organism Sinorhizobium garamanticum strain LMG 24692

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PZN02_RS28040 Protein ID WP_280662207.1
Coordinates 1765524..1765799 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PZN02_RS28045 Protein ID WP_280662208.1
Coordinates 1765799..1766059 (-) Length 87 a.a.

Genomic Context

PZN02_RS28025PZN02_RS28030PZN02_RS28035PZN02_RS28020PZN02_RS28040PZN02_RS28045PZN02_RS28050PZN02_RS28055PZN02_RS28060PZN02_RS28065PZN02_RS28070PZN02_RS28075
Location: 1761669..1764506 (2838 bp)
Type: Others
Protein ID: WP_280662204.1
Location: 1764661..1764894 (234 bp)
Type: Others
Protein ID: WP_280662205.1
Location: 1764891..1765295 (405 bp)
Type: Others
Protein ID: WP_280662206.1
Location: 1760844..1761248 (405 bp)
Type: Others
Protein ID: WP_280662203.1
Location: 1765524..1765799 (276 bp)
Type: Toxin
Protein ID: WP_280662207.1
Location: 1765799..1766059 (261 bp)
Type: Antitoxin
Protein ID: WP_280662208.1
Location: 1766151..1767038 (888 bp)
Type: Others
Protein ID: WP_280662209.1
Location: 1767035..1767820 (786 bp)
Type: Others
Protein ID: WP_280662210.1
Location: 1767831..1768418 (588 bp)
Type: Others
Protein ID: WP_280663306.1
Location: 1768569..1769159 (591 bp)
Type: Others
Protein ID: WP_280662211.1
Location: 1769313..1769450 (138 bp)
Type: Others
Protein ID: WP_280663307.1
Location: 1769641..1770237 (597 bp)
Type: Others
Protein ID: WP_280662212.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PZN02_RS28020 (PZN02_005606)1760844..1761248-405WP_280662203.1DoxX family protein-
PZN02_RS28025 (PZN02_005607)1761669..1764506+2838WP_280662204.1DNA translocase FtsK-
PZN02_RS28030 (PZN02_005608)1764661..1764894+234WP_280662205.1AbrB/MazE/SpoVT family DNA-binding domain-containing protein-
PZN02_RS28035 (PZN02_005609)1764891..1765295+405WP_280662206.1type II toxin-antitoxin system VapC family toxin-
PZN02_RS28040 (PZN02_005610)1765524..1765799-276WP_280662207.1type II toxin-antitoxin system RelE/ParE family toxinToxin
PZN02_RS28045 (PZN02_005611)1765799..1766059-261WP_280662208.1ribbon-helix-helix domain-containing proteinAntitoxin
PZN02_RS28050 (PZN02_005612)1766151..1767038-888WP_280662209.1SDR family NAD(P)-dependent oxidoreductase-
PZN02_RS28055 (PZN02_005613)1767035..1767820-786WP_280662210.1hypothetical protein-
PZN02_RS28060 (PZN02_005614)1767831..1768418-588WP_280663306.1protein-S-isoprenylcysteine O-methyltransferase-
PZN02_RS28065 (PZN02_005615)1768569..1769159-591WP_280662211.1hypothetical protein-
PZN02_RS28070 (PZN02_005616)1769313..1769450-138WP_280663307.1ABC transporter-
PZN02_RS28075 (PZN02_005617)1769641..1770237-597WP_280662212.1L,D-transpeptidase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10908.52 Da        Isoelectric Point: 10.2942

>T274935 WP_280662207.1 NZ_CP120374:c1765799-1765524 [Sinorhizobium garamanticum]
MKLHWTTKSVSDLGRLYDFLAPVNRQAEARTVQALASAPRRLLEQPRIGERLEEFDPRAVRRILVSHYEMRYEITQSTIY
VLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9615.98 Da        Isoelectric Point: 5.5959

>AT274935 WP_280662208.1 NZ_CP120374:c1766059-1765799 [Sinorhizobium garamanticum]
METKVLTAHVPLPLAEKVDQIAARLERSRGWIVKQALTAWIDQEEERRRLTLEALANVDGGHVVSHQSVQAWADSLDSDK
PLPLPL

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References