Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1765524..1766059 Replicon chromosome
Accession NZ_CP120374
Organism Sinorhizobium garamanticum strain LMG 24692

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PZN02_RS28040 Protein ID WP_280662207.1
Coordinates 1765524..1765799 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PZN02_RS28045 Protein ID WP_280662208.1
Coordinates 1765799..1766059 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PZN02_RS28020 (PZN02_005606) 1760844..1761248 - 405 WP_280662203.1 DoxX family protein -
PZN02_RS28025 (PZN02_005607) 1761669..1764506 + 2838 WP_280662204.1 DNA translocase FtsK -
PZN02_RS28030 (PZN02_005608) 1764661..1764894 + 234 WP_280662205.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
PZN02_RS28035 (PZN02_005609) 1764891..1765295 + 405 WP_280662206.1 type II toxin-antitoxin system VapC family toxin -
PZN02_RS28040 (PZN02_005610) 1765524..1765799 - 276 WP_280662207.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PZN02_RS28045 (PZN02_005611) 1765799..1766059 - 261 WP_280662208.1 ribbon-helix-helix domain-containing protein Antitoxin
PZN02_RS28050 (PZN02_005612) 1766151..1767038 - 888 WP_280662209.1 SDR family NAD(P)-dependent oxidoreductase -
PZN02_RS28055 (PZN02_005613) 1767035..1767820 - 786 WP_280662210.1 hypothetical protein -
PZN02_RS28060 (PZN02_005614) 1767831..1768418 - 588 WP_280663306.1 protein-S-isoprenylcysteine O-methyltransferase -
PZN02_RS28065 (PZN02_005615) 1768569..1769159 - 591 WP_280662211.1 hypothetical protein -
PZN02_RS28070 (PZN02_005616) 1769313..1769450 - 138 WP_280663307.1 ABC transporter -
PZN02_RS28075 (PZN02_005617) 1769641..1770237 - 597 WP_280662212.1 L,D-transpeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10908.52 Da        Isoelectric Point: 10.2942

>T274935 WP_280662207.1 NZ_CP120374:c1765799-1765524 [Sinorhizobium garamanticum]
MKLHWTTKSVSDLGRLYDFLAPVNRQAEARTVQALASAPRRLLEQPRIGERLEEFDPRAVRRILVSHYEMRYEITQSTIY
VLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9615.98 Da        Isoelectric Point: 5.5959

>AT274935 WP_280662208.1 NZ_CP120374:c1766059-1765799 [Sinorhizobium garamanticum]
METKVLTAHVPLPLAEKVDQIAARLERSRGWIVKQALTAWIDQEEERRRLTLEALANVDGGHVVSHQSVQAWADSLDSDK
PLPLPL

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References