Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1629370..1630010 Replicon chromosome
Accession NZ_CP120374
Organism Sinorhizobium garamanticum strain LMG 24692

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PZN02_RS27450 Protein ID WP_280662097.1
Coordinates 1629370..1629756 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PZN02_RS27455 Protein ID WP_280662098.1
Coordinates 1629756..1630010 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PZN02_RS27420 (PZN02_005486) 1625181..1625948 + 768 WP_280662092.1 3-hydroxyacyl-CoA dehydrogenase -
PZN02_RS27425 (PZN02_005487) 1626041..1626298 - 258 WP_280662093.1 DUF1127 domain-containing protein -
PZN02_RS27430 (PZN02_005488) 1626410..1627918 + 1509 WP_280662094.1 winged helix-turn-helix domain-containing tetratricopeptide repeat protein -
PZN02_RS27435 (PZN02_005489) 1628059..1628451 - 393 WP_280662095.1 GFA family protein -
PZN02_RS27440 (PZN02_005490) 1628694..1628987 + 294 WP_280662096.1 DUF2934 domain-containing protein -
PZN02_RS27445 (PZN02_005491) 1629115..1629326 - 212 Protein_1492 integrase -
PZN02_RS27450 (PZN02_005492) 1629370..1629756 - 387 WP_280662097.1 type II toxin-antitoxin system VapC family toxin Toxin
PZN02_RS27455 (PZN02_005493) 1629756..1630010 - 255 WP_280662098.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PZN02_RS27460 (PZN02_005494) 1630321..1631466 - 1146 WP_280662099.1 HPP family protein -
PZN02_RS27465 (PZN02_005495) 1631661..1631993 + 333 WP_280662100.1 hypothetical protein -
PZN02_RS27470 (PZN02_005496) 1632210..1633286 - 1077 WP_280662101.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14018.93 Da        Isoelectric Point: 4.6381

>T274934 WP_280662097.1 NZ_CP120374:c1629756-1629370 [Sinorhizobium garamanticum]
MVIDTSAIVALAFNEPEAETYERKVVDAPRRFISAATVLELAIVIEARLGEAGAAELDLWLYKAGVEIVAVDAEQIAVAR
RAWRSYGKGRHPAGLNYGDCFSYALAKTRNEPLLFKGDDFSRTDIEAA

Download         Length: 387 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9378.61 Da        Isoelectric Point: 4.9011

>AT274934 WP_280662098.1 NZ_CP120374:c1630010-1629756 [Sinorhizobium garamanticum]
MALSIKDLETERLAKALAEKTGETITMATRRALEERLRRLANAGNRDVLLEELAASRGRWGKLPVLDNRSADEILEYDEN
GAPN

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References