Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 1269052..1269982 Replicon chromosome
Accession NZ_CP120374
Organism Sinorhizobium garamanticum strain LMG 24692

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PZN02_RS25725 Protein ID WP_280663281.1
Coordinates 1269052..1269543 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PZN02_RS25730 Protein ID WP_280661795.1
Coordinates 1269611..1269982 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PZN02_RS25700 (PZN02_005142) 1264237..1265097 + 861 WP_280661790.1 sulfate ABC transporter permease subunit CysT -
PZN02_RS25705 (PZN02_005143) 1265087..1265974 + 888 WP_280661791.1 sulfate ABC transporter permease subunit CysW -
PZN02_RS25710 (PZN02_005144) 1265990..1267099 + 1110 WP_280661792.1 sulfate/molybdate ABC transporter ATP-binding protein -
PZN02_RS25715 (PZN02_005145) 1267220..1268602 + 1383 WP_280661793.1 FAD-binding oxidoreductase -
PZN02_RS25720 (PZN02_005146) 1268657..1269022 + 366 WP_280661794.1 SMI1/KNR4 family protein -
PZN02_RS25725 (PZN02_005147) 1269052..1269543 - 492 WP_280663281.1 RES family NAD+ phosphorylase Toxin
PZN02_RS25730 (PZN02_005148) 1269611..1269982 - 372 WP_280661795.1 DUF2384 domain-containing protein Antitoxin
PZN02_RS25735 (PZN02_005149) 1270064..1270846 - 783 WP_280661796.1 crotonase/enoyl-CoA hydratase family protein -
PZN02_RS25740 (PZN02_005150) 1270843..1271712 - 870 WP_280661797.1 hydroxymethylglutaryl-CoA lyase -
PZN02_RS25745 (PZN02_005151) 1271709..1273697 - 1989 WP_280661798.1 acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha -
PZN02_RS25750 (PZN02_005152) 1273715..1274098 - 384 WP_280661799.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-156)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18066.52 Da        Isoelectric Point: 5.5643

>T274933 WP_280663281.1 NZ_CP120374:c1269543-1269052 [Sinorhizobium garamanticum]
MPLWRAFVPRWAHAPLSGEGAARFGGRWNPVGVPTIYAARELSTAWAEYNQGFVQHPALIVRLELYDARLADLTDANVLA
ELGLTDAIHRCEWRDDLDKGVVPQTHEVQADLLAQEFHGVIYPSFMSPGGTCVALWRWNGAGAPRLEVIDPEGRLPKSPA
SWV

Download         Length: 492 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13075.19 Da        Isoelectric Point: 9.6554

>AT274933 WP_280661795.1 NZ_CP120374:c1269982-1269611 [Sinorhizobium garamanticum]
MVALNLDIPAARFGEDHSPFLSARLVADRLGITLAELAKLIGVARNTLTAKTGARKVDSALSNVVRILSMASEMAGDEAR
AVIWFKHQPIPGWAGKTAFDLVGEGKADKVLAYLEAVRAGVYA

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References