Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/NGN_SP-Phd
Location 163189..163850 Replicon plasmid unnamed
Accession NZ_CP120372
Organism Sinorhizobium numidicum strain LMG 27395

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYH38_RS29920 Protein ID WP_280736488.1
Coordinates 163189..163596 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYH38_RS29925 Protein ID WP_280736490.1
Coordinates 163596..163850 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH38_RS29895 (PYH38_005979) 158945..159859 + 915 WP_280736483.1 nucleotidyltransferase and HEPN domain-containing protein -
PYH38_RS29900 (PYH38_005980) 159877..160275 - 399 WP_280736649.1 hypothetical protein -
PYH38_RS29905 (PYH38_005981) 160181..161098 - 918 WP_280736484.1 recombinase family protein -
PYH38_RS29910 (PYH38_005982) 161699..161950 - 252 WP_280736485.1 hypothetical protein -
PYH38_RS29915 (PYH38_005983) 162077..163066 - 990 WP_280736615.1 site-specific integrase -
PYH38_RS29920 (PYH38_005984) 163189..163596 - 408 WP_280736488.1 type II toxin-antitoxin system VapC family toxin Toxin
PYH38_RS29925 (PYH38_005985) 163596..163850 - 255 WP_280736490.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PYH38_RS29930 (PYH38_005986) 164086..165039 + 954 WP_280736491.1 DUF1403 family protein -
PYH38_RS29935 (PYH38_005987) 165042..165731 + 690 WP_280663344.1 SMC-Scp complex subunit ScpB -
PYH38_RS29940 (PYH38_005988) 166017..166337 + 321 WP_280736616.1 DUF1476 domain-containing protein -
PYH38_RS29945 (PYH38_005989) 166628..167089 + 462 WP_280736492.1 hypothetical protein -
PYH38_RS29950 (PYH38_005990) 167211..167489 - 279 WP_280663341.1 hypothetical protein -
PYH38_RS29955 (PYH38_005991) 167632..168072 - 441 WP_280663340.1 DUF2267 domain-containing protein -
PYH38_RS29960 (PYH38_005992) 168286..168597 - 312 Protein_160 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB 1..629446 629446
- flank IS/Tn - - 168274..168597 323


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-60)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14884.11 Da        Isoelectric Point: 6.6458

>T274931 WP_280736488.1 NZ_CP120372:c163596-163189 [Sinorhizobium numidicum]
MYLVDTNIVSEARRGAPQAVAWLRSVDPLSIHLSALTLGEIMRGIALKQKSDPKAAAHLAEWLRKLRHDHGDRILPVTDQ
IAVEWGRIAAIRPRGDIDGLLAATAVVHDLILVTRNVKDFEDTDASVINPWETPA

Download         Length: 408 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9334.46 Da        Isoelectric Point: 5.5940

>AT274931 WP_280736490.1 NZ_CP120372:c163850-163596 [Sinorhizobium numidicum]
MEWQLQDAKNHFSKVVQKARHEGPQIVTLRGERTAVVLSAHDYDALRAGRPTLVDDLLGGPPWDDELADAVEARAKTPSR
DVAF

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References