Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 586769..587430 Replicon chromosome
Accession NZ_CP120370
Organism Sinorhizobium numidicum strain LMG 27395

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PYH38_RS02875 Protein ID WP_280731929.1
Coordinates 586769..587206 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYH38_RS02880 Protein ID WP_280731930.1
Coordinates 587203..587430 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH38_RS02855 (PYH38_000570) 582913..583074 + 162 WP_280731926.1 hypothetical protein -
PYH38_RS02860 (PYH38_000571) 583535..584680 + 1146 Protein_571 Fic family protein -
PYH38_RS02865 (PYH38_000572) 584631..585584 - 954 WP_280731927.1 IS481 family transposase -
PYH38_RS02870 (PYH38_000573) 585954..586604 + 651 WP_280731928.1 glutathione S-transferase family protein -
PYH38_RS02875 (PYH38_000574) 586769..587206 - 438 WP_280731929.1 PIN domain-containing protein Toxin
PYH38_RS02880 (PYH38_000575) 587203..587430 - 228 WP_280731930.1 CopG family transcriptional regulator Antitoxin
PYH38_RS02885 (PYH38_000576) 588016..588645 + 630 WP_280731931.1 response regulator transcription factor -
PYH38_RS02890 (PYH38_000577) 588824..590014 + 1191 WP_280731932.1 aminotransferase class V-fold PLP-dependent enzyme -
PYH38_RS02895 (PYH38_000578) 590037..590981 + 945 WP_280731933.1 CoA ester lyase -
PYH38_RS02900 (PYH38_000579) 590994..592178 + 1185 WP_280731935.1 malate--CoA ligase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 584631..585584 953


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15244.48 Da        Isoelectric Point: 6.9661

>T274928 WP_280731929.1 NZ_CP120370:c587206-586769 [Sinorhizobium numidicum]
VTFLLDVNVLIALIDPGHVAHDDAHDWFASIGQTAWATCPITENGVIRIVGNAKYPNSPGSPSLVMEIVGKLRSLPGHCF
WPDDVSLVGSGDIAATKILTSGQVTDTYLLALAKAHGGQLATFDRKLSAAAVTRGNAALRLITSK

Download         Length: 438 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8179.41 Da        Isoelectric Point: 9.1311

>AT274928 WP_280731930.1 NZ_CP120370:c587430-587203 [Sinorhizobium numidicum]
MRTTLAIDDDVLIAAKAMAAQQHRSVGEVISELARRSLRRPRSGGERNGIPLLSPRPDAPPVTLEIVNALRDELP

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References