Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 301255..301829 Replicon chromosome
Accession NZ_CP120370
Organism Sinorhizobium numidicum strain LMG 27395

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PYH38_RS01425 Protein ID WP_280731678.1
Coordinates 301255..301638 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYH38_RS01430 Protein ID WP_280731679.1
Coordinates 301635..301829 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH38_RS01400 (PYH38_000280) 296729..297985 + 1257 WP_280731674.1 ribulose-bisphosphate carboxylase large subunit family protein -
PYH38_RS01405 (PYH38_000281) 298019..299353 + 1335 WP_280731676.1 four-carbon acid sugar kinase family protein -
PYH38_RS01410 (PYH38_000282) 299551..299654 - 104 Protein_281 TetR/AcrR family transcriptional regulator -
PYH38_RS01415 (PYH38_000283) 299903..300238 + 336 WP_280731677.1 RidA family protein -
PYH38_RS01420 (PYH38_000284) 300551..300765 - 215 Protein_283 transposase -
PYH38_RS01425 (PYH38_000285) 301255..301638 - 384 WP_280731678.1 type II toxin-antitoxin system VapC family toxin Toxin
PYH38_RS01430 (PYH38_000286) 301635..301829 - 195 WP_280731679.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PYH38_RS01435 (PYH38_000287) 302731..303795 + 1065 WP_280731680.1 class I SAM-dependent methyltransferase -
PYH38_RS01440 (PYH38_000288) 304191..304604 - 414 WP_280731681.1 GNAT family N-acetyltransferase -
PYH38_RS01445 (PYH38_000289) 304760..305785 - 1026 WP_280731682.1 LacI family DNA-binding transcriptional regulator -
PYH38_RS01450 (PYH38_000290) 305835..306161 - 327 WP_280731683.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14223.39 Da        Isoelectric Point: 6.2148

>T274927 WP_280731678.1 NZ_CP120370:c301638-301255 [Sinorhizobium numidicum]
VRLADTGIWIDHFRLADPQLIQTIENDMLLCHPAIVGELALGSLHNRLVTLGFLAVQREVIIATHDEVMAMIDEHQLYSM
GIGYTDAHLLASTLIDSRAELWTRDKRLRRAAEKARARVVSDGTVPN

Download         Length: 384 bp

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 6926.06 Da        Isoelectric Point: 10.5929

>AT274927 WP_280731679.1 NZ_CP120370:c301829-301635 [Sinorhizobium numidicum]
MRSTINIDDSLMEKAKALTGTKETAAVVRQALETLVRMEAGKRLIALGGTMPDAEAGPRRRAEK

Download         Length: 195 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References