Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/NGN_SP-Phd
Location 601164..601825 Replicon plasmid unnamed
Accession NZ_CP120369
Organism Sinorhizobium numidicum strain CIP 109850

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYH37_RS32005 Protein ID WP_280736488.1
Coordinates 601418..601825 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYH37_RS32000 Protein ID WP_280736490.1
Coordinates 601164..601418 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH37_RS31965 (PYH37_006392) 596417..596728 + 312 Protein_560 ATP-binding protein -
PYH37_RS31970 (PYH37_006393) 596942..597382 + 441 WP_280663340.1 DUF2267 domain-containing protein -
PYH37_RS31975 (PYH37_006394) 597525..597803 + 279 WP_280663341.1 hypothetical protein -
PYH37_RS31980 (PYH37_006395) 597925..598386 - 462 WP_280736492.1 hypothetical protein -
PYH37_RS31985 (PYH37_006396) 598677..598997 - 321 WP_280736616.1 DUF1476 domain-containing protein -
PYH37_RS31990 (PYH37_006397) 599283..599972 - 690 WP_280663344.1 SMC-Scp complex subunit ScpB -
PYH37_RS31995 (PYH37_006398) 599975..600928 - 954 WP_280736491.1 DUF1403 family protein -
PYH37_RS32000 (PYH37_006399) 601164..601418 + 255 WP_280736490.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PYH37_RS32005 (PYH37_006400) 601418..601825 + 408 WP_280736488.1 type II toxin-antitoxin system VapC family toxin Toxin
PYH37_RS32010 (PYH37_006401) 601948..602937 + 990 WP_280736615.1 site-specific integrase -
PYH37_RS32015 (PYH37_006402) 603064..603315 + 252 WP_280736485.1 hypothetical protein -
PYH37_RS32020 (PYH37_006403) 603916..604833 + 918 WP_280736484.1 recombinase family protein -
PYH37_RS32025 (PYH37_006404) 604940..605137 + 198 WP_280736711.1 hypothetical protein -
PYH37_RS32030 (PYH37_006405) 605155..606069 - 915 WP_280736483.1 nucleotidyltransferase and HEPN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB 1..629445 629445
- flank IS/Tn - - 596417..596740 323


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-60)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14884.11 Da        Isoelectric Point: 6.6458

>T274926 WP_280736488.1 NZ_CP120369:601418-601825 [Sinorhizobium numidicum]
MYLVDTNIVSEARRGAPQAVAWLRSVDPLSIHLSALTLGEIMRGIALKQKSDPKAAAHLAEWLRKLRHDHGDRILPVTDQ
IAVEWGRIAAIRPRGDIDGLLAATAVVHDLILVTRNVKDFEDTDASVINPWETPA

Download         Length: 408 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9334.46 Da        Isoelectric Point: 5.5940

>AT274926 WP_280736490.1 NZ_CP120369:601164-601418 [Sinorhizobium numidicum]
MEWQLQDAKNHFSKVVQKARHEGPQIVTLRGERTAVVLSAHDYDALRAGRPTLVDDLLGGPPWDDELADAVEARAKTPSR
DVAF

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References