Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 584749..585410 Replicon chromosome
Accession NZ_CP120367
Organism Sinorhizobium numidicum strain CIP 109850

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PYH37_RS02865 Protein ID WP_280731929.1
Coordinates 584749..585186 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYH37_RS02870 Protein ID WP_280731930.1
Coordinates 585183..585410 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH37_RS02845 (PYH37_000568) 580893..581054 + 162 WP_280731926.1 hypothetical protein -
PYH37_RS02850 (PYH37_000569) 581515..582660 + 1146 Protein_569 Fic family protein -
PYH37_RS02855 (PYH37_000570) 582611..583564 - 954 WP_280731927.1 IS481 family transposase -
PYH37_RS02860 (PYH37_000571) 583934..584584 + 651 WP_280731928.1 glutathione S-transferase family protein -
PYH37_RS02865 (PYH37_000572) 584749..585186 - 438 WP_280731929.1 PIN domain-containing protein Toxin
PYH37_RS02870 (PYH37_000573) 585183..585410 - 228 WP_280731930.1 CopG family transcriptional regulator Antitoxin
PYH37_RS02875 (PYH37_000574) 585996..586625 + 630 WP_280731931.1 response regulator transcription factor -
PYH37_RS02880 (PYH37_000575) 586804..587994 + 1191 WP_280731932.1 aminotransferase class V-fold PLP-dependent enzyme -
PYH37_RS02885 (PYH37_000576) 588017..588961 + 945 WP_280731933.1 CoA ester lyase -
PYH37_RS02890 (PYH37_000577) 588974..590158 + 1185 WP_280731935.1 malate--CoA ligase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 582611..583564 953


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15244.48 Da        Isoelectric Point: 6.9661

>T274922 WP_280731929.1 NZ_CP120367:c585186-584749 [Sinorhizobium numidicum]
VTFLLDVNVLIALIDPGHVAHDDAHDWFASIGQTAWATCPITENGVIRIVGNAKYPNSPGSPSLVMEIVGKLRSLPGHCF
WPDDVSLVGSGDIAATKILTSGQVTDTYLLALAKAHGGQLATFDRKLSAAAVTRGNAALRLITSK

Download         Length: 438 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8179.41 Da        Isoelectric Point: 9.1311

>AT274922 WP_280731930.1 NZ_CP120367:c585410-585183 [Sinorhizobium numidicum]
MRTTLAIDDDVLIAAKAMAAQQHRSVGEVISELARRSLRRPRSGGERNGIPLLSPRPDAPPVTLEIVNALRDELP

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References