Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 299235..299809 Replicon chromosome
Accession NZ_CP120367
Organism Sinorhizobium numidicum strain CIP 109850

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PYH37_RS01415 Protein ID WP_280731678.1
Coordinates 299235..299618 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PYH37_RS01420 Protein ID WP_280731679.1
Coordinates 299615..299809 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH37_RS01390 (PYH37_000278) 294709..295965 + 1257 WP_280731674.1 ribulose-bisphosphate carboxylase large subunit family protein -
PYH37_RS01395 (PYH37_000279) 295999..297333 + 1335 WP_280731676.1 four-carbon acid sugar kinase family protein -
PYH37_RS01400 (PYH37_000280) 297531..297634 - 104 Protein_279 TetR/AcrR family transcriptional regulator -
PYH37_RS01405 (PYH37_000281) 297883..298218 + 336 WP_280731677.1 RidA family protein -
PYH37_RS01410 (PYH37_000282) 298531..298745 - 215 Protein_281 transposase -
PYH37_RS01415 (PYH37_000283) 299235..299618 - 384 WP_280731678.1 type II toxin-antitoxin system VapC family toxin Toxin
PYH37_RS01420 (PYH37_000284) 299615..299809 - 195 WP_280731679.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PYH37_RS01425 (PYH37_000285) 300711..301775 + 1065 WP_280731680.1 class I SAM-dependent methyltransferase -
PYH37_RS01430 (PYH37_000286) 302171..302584 - 414 WP_280731681.1 GNAT family N-acetyltransferase -
PYH37_RS01435 (PYH37_000287) 302740..303765 - 1026 WP_280731682.1 LacI family DNA-binding transcriptional regulator -
PYH37_RS01440 (PYH37_000288) 303815..304141 - 327 WP_280731683.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14223.39 Da        Isoelectric Point: 6.2148

>T274921 WP_280731678.1 NZ_CP120367:c299618-299235 [Sinorhizobium numidicum]
VRLADTGIWIDHFRLADPQLIQTIENDMLLCHPAIVGELALGSLHNRLVTLGFLAVQREVIIATHDEVMAMIDEHQLYSM
GIGYTDAHLLASTLIDSRAELWTRDKRLRRAAEKARARVVSDGTVPN

Download         Length: 384 bp

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 6926.06 Da        Isoelectric Point: 10.5929

>AT274921 WP_280731679.1 NZ_CP120367:c299809-299615 [Sinorhizobium numidicum]
MRSTINIDDSLMEKAKALTGTKETAAVVRQALETLVRMEAGKRLIALGGTMPDAEAGPRRRAEK

Download         Length: 195 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References