Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 19820..20631 Replicon plasmid unnamed2
Accession NZ_CP120363
Organism Chelativorans sp. AA-79

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag PVE73_RS27225 Protein ID WP_277367890.1
Coordinates 19820..20356 (-) Length 179 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag PVE73_RS27230 Protein ID WP_277367891.1
Coordinates 20353..20631 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVE73_RS27195 (PVE73_27195) 14894..15313 - 420 WP_277367884.1 hypothetical protein -
PVE73_RS27200 (PVE73_27200) 15393..16310 - 918 WP_277367885.1 hypothetical protein -
PVE73_RS27205 (PVE73_27205) 16875..17792 - 918 WP_277367886.1 zincin-like metallopeptidase domain-containing protein -
PVE73_RS27210 (PVE73_27210) 18013..18543 + 531 WP_277367887.1 hypothetical protein -
PVE73_RS27215 (PVE73_27215) 18695..19192 + 498 WP_277367888.1 MucR family transcriptional regulator -
PVE73_RS27220 (PVE73_27220) 19203..19796 + 594 WP_277367889.1 SOS response-associated peptidase family protein -
PVE73_RS27225 (PVE73_27225) 19820..20356 - 537 WP_277367890.1 GNAT family N-acetyltransferase Toxin
PVE73_RS27230 (PVE73_27230) 20353..20631 - 279 WP_277367891.1 DUF1778 domain-containing protein Antitoxin
PVE73_RS27235 (PVE73_27235) 20749..24012 - 3264 WP_277367892.1 error-prone DNA polymerase -
PVE73_RS27240 (PVE73_27240) 24009..25529 - 1521 WP_277367893.1 DNA polymerase Y family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..219481 219481


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(14-87)


Sequences

Toxin        


Download         Length: 179 a.a.        Molecular weight: 19100.84 Da        Isoelectric Point: 8.4742

>T274901 WP_277367890.1 NZ_CP120363:c20356-19820 [Chelativorans sp. AA-79]
MTLPDWREEPIAKAHDRKGFDCGQPELNDFLMRYARQASESGASKTYVAVDSGNRTTILGFYTLSPAQIDFEAVPDVARP
AGGGRHAIGGFRLGRLAVATAHQGHGLGGELLIAAARRCIRASTEVGGTLLFIDAKDERAAAWYRSYGAVTIPKAPLSLV
LPYSVFIAVMEQAGKPII

Download         Length: 537 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10363.08 Da        Isoelectric Point: 11.1585

>AT274901 WP_277367891.1 NZ_CP120363:c20631-20353 [Chelativorans sp. AA-79]
MPRAAAENTSRFPMQIPPADKARLMRAAALERTSLKEFVLRNALQAAEIVIERAERVTLDEEQTRFMLDLLDHPPAPNAK
LRKAARSLAARK

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References