274900

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3225661..3226147 Replicon chromosome
Accession NZ_CP120361
Organism Chelativorans sp. AA-79

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag PVE73_RS15775 Protein ID WP_277363156.1
Coordinates 3225878..3226147 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag PVE73_RS15770 Protein ID WP_277363155.1
Coordinates 3225661..3225894 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVE73_RS15740 (PVE73_15740) 3220960..3221325 - 366 WP_277363152.1 NADH-quinone oxidoreductase subunit A -
PVE73_RS15745 (PVE73_15745) 3221709..3222980 + 1272 WP_277363153.1 winged helix-turn-helix domain-containing protein -
PVE73_RS15750 (PVE73_15750) 3222999..3223163 - 165 WP_277367474.1 biotin/lipoyl-containing protein -
PVE73_RS15755 (PVE73_15755) 3223138..3223197 - 60 Protein_3111 hypothetical protein -
PVE73_RS15760 (PVE73_15760) 3223290..3225011 - 1722 Protein_3112 acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha -
PVE73_RS15765 (PVE73_15765) 3225138..3225596 + 459 WP_277363154.1 YaiI/YqxD family protein -
PVE73_RS15770 (PVE73_15770) 3225661..3225894 + 234 WP_277363155.1 DUF6290 family protein Antitoxin
PVE73_RS15775 (PVE73_15775) 3225878..3226147 + 270 WP_277363156.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PVE73_RS15780 (PVE73_15780) 3226492..3227586 + 1095 WP_277363157.1 glycine cleavage system aminomethyltransferase GcvT -
PVE73_RS15785 (PVE73_15785) 3227591..3227959 + 369 WP_277363158.1 glycine cleavage system protein GcvH -
PVE73_RS15790 (PVE73_15790) 3227970..3230765 + 2796 WP_277363159.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10634.42 Da        Isoelectric Point: 10.5737

>T274900 WP_277363156.1 NZ_CP120361:3225878-3226147 [Chelativorans sp. AA-79]
MTWTIEVDDAALRQLKKIGRVESKRIYGFLRERIATLDNPRKLGAALQGSRFEHLWRYRVGDYRIICDIQDHKLVVLVLQ
IGHRREIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 9191.27 Da        Isoelectric Point: 4.4663

>AT274900 WP_277363155.1 NZ_CP120361:3225661-3225894 [Chelativorans sp. AA-79]
MSKQTALRLPDETYERLRVLSERTGRTAAYYMRQAIEQHLEDLEDIYLAEQVLERLKRGESRTYTLAEVERELDLDD

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References