Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 828392..829056 Replicon chromosome
Accession NZ_CP120361
Organism Chelativorans sp. AA-79

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PVE73_RS04200 Protein ID WP_277365739.1
Coordinates 828649..829056 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag PVE73_RS04195 Protein ID WP_277365738.1
Coordinates 828392..828652 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVE73_RS04170 (PVE73_04170) 824409..824774 - 366 WP_277365735.1 hydroxyisourate hydrolase -
PVE73_RS04175 (PVE73_04175) 824950..826383 + 1434 WP_277367341.1 allantoinase PuuE -
PVE73_RS04180 (PVE73_04180) 826380..827213 + 834 WP_277365736.1 bifunctional allantoicase/(S)-ureidoglycine aminohydrolase -
PVE73_RS04185 (PVE73_04185) 827235..827735 + 501 WP_277367342.1 ureidoglycolate lyase -
PVE73_RS04190 (PVE73_04190) 827732..828331 + 600 WP_277365737.1 nucleoside deaminase -
PVE73_RS04195 (PVE73_04195) 828392..828652 + 261 WP_277365738.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PVE73_RS04200 (PVE73_04200) 828649..829056 + 408 WP_277365739.1 type II toxin-antitoxin system VapC family toxin Toxin
PVE73_RS04205 (PVE73_04205) 829154..830359 - 1206 WP_277365740.1 3-oxoadipyl-CoA thiolase -
PVE73_RS04210 (PVE73_04210) 830352..831164 - 813 WP_277365741.1 CoA-transferase subunit beta -
PVE73_RS04215 (PVE73_04215) 831161..832018 - 858 WP_277365742.1 CoA-transferase -
PVE73_RS04220 (PVE73_04220) 832076..832870 + 795 WP_277365743.1 IclR family transcriptional regulator C-terminal domain-containing protein -
PVE73_RS04225 (PVE73_04225) 832894..833118 - 225 WP_277365744.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-123)

Antitoxin

SpoVT-AbrB domain

(8-58)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14923.30 Da        Isoelectric Point: 9.0921

>T274897 WP_277365739.1 NZ_CP120361:828649-829056 [Chelativorans sp. AA-79]
MKPPFMLDTNVVSAFMHGRSRALDRRISAYGKDDLCVSVVSYGETRYGLALRPGAKHLAAAAELLFGLVKISPWTPEAAC
RYGEMRAELRRRGRTMQPLDMLIAAHALEAGATLVTSDRAFRFVPGLAVENWLDD

Download         Length: 408 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 10096.27 Da        Isoelectric Point: 4.7266

>AT274897 WP_277365738.1 NZ_CP120361:828392-828652 [Chelativorans sp. AA-79]
MPRTAKLFWNGRSQAVRLPAEFRFEGDEVEIRRDPATGDVVLSPKPQRTGSWDRFFRLRDQIPPEELEGFMEDREQGLHE
RDDPLA

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References