Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 122161..122713 Replicon chromosome
Accession NZ_CP120360
Organism Janibacter sp. DB-40

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PVE36_RS00635 Protein ID WP_277453912.1
Coordinates 122161..122475 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PVE36_RS00640 Protein ID WP_277453914.1
Coordinates 122480..122713 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVE36_RS00615 117510..118921 + 1412 Protein_119 FGGY family carbohydrate kinase -
PVE36_RS00620 118942..119979 - 1038 WP_277453909.1 zinc-dependent alcohol dehydrogenase family protein -
PVE36_RS00625 120035..121369 + 1335 WP_277453910.1 alpha-hydroxy-acid oxidizing protein -
PVE36_RS00630 121399..122109 - 711 WP_277453911.1 4a-hydroxytetrahydrobiopterin dehydratase -
PVE36_RS00635 122161..122475 - 315 WP_277453912.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PVE36_RS00640 122480..122713 - 234 WP_277453914.1 ribbon-helix-helix domain-containing protein Antitoxin
PVE36_RS00645 122793..124316 - 1524 WP_277453916.1 fused MFS/spermidine synthase -
PVE36_RS00650 124361..125137 + 777 WP_277453918.1 hypothetical protein -
PVE36_RS00655 125208..126392 + 1185 WP_277453919.1 TIGR04053 family radical SAM/SPASM domain-containing protein -
PVE36_RS00660 126415..127629 - 1215 WP_277453920.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-93)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11058.81 Da        Isoelectric Point: 5.0937

>T274896 WP_277453912.1 NZ_CP120360:c122475-122161 [Janibacter sp. DB-40]
VREICLVRLDKTRPALVLTRETARGAMTKVTLAPITTTIKGLSSEVRVGPANGLDQDCAVALDNVVTVPVERLGRTVGYL
SAAQEDELARAVVLAYDLDLPLSG

Download         Length: 315 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8516.58 Da        Isoelectric Point: 4.4523

>AT274896 WP_277453914.1 NZ_CP120360:c122713-122480 [Janibacter sp. DB-40]
MSIQIAVRLPDEMVEFLDREVASGRVTSRAALVTSALEREMRRLAAEHDVALLHERGTADDLDDLVTWTSTHVGLGD

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References