Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 4565272..4565813 Replicon chromosome
Accession NZ_CP120359
Organism Pseudomonas sp. AA-38

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PVE35_RS21035 Protein ID WP_277372878.1
Coordinates 4565517..4565813 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PVE35_RS21030 Protein ID WP_277372877.1
Coordinates 4565272..4565529 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVE35_RS21005 4560412..4561443 - 1032 WP_277372873.1 ABC transporter ATP-binding protein -
PVE35_RS21010 4561440..4562234 - 795 WP_277372874.1 ABC transporter permease subunit -
PVE35_RS21015 4562231..4563088 - 858 WP_277374917.1 ABC transporter permease -
PVE35_RS21020 4563102..4564106 - 1005 WP_277372875.1 ABC transporter substrate-binding protein -
PVE35_RS21025 4564090..4565109 - 1020 WP_277372876.1 substrate-binding domain-containing protein -
PVE35_RS21030 4565272..4565529 + 258 WP_277372877.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PVE35_RS21035 4565517..4565813 + 297 WP_277372878.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PVE35_RS21040 4565817..4567136 - 1320 WP_277372879.1 metallopeptidase TldD-related protein -
PVE35_RS21045 4567136..4568578 - 1443 WP_277372880.1 TldD/PmbA family protein -
PVE35_RS21050 4568675..4569238 - 564 WP_277372881.1 TetR/AcrR family transcriptional regulator -
PVE35_RS21055 4569418..4570080 + 663 WP_277374918.1 glutathione S-transferase -
PVE35_RS21060 4570334..4570477 - 144 WP_268184384.1 DUF2474 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11185.11 Da        Isoelectric Point: 6.2284

>T274895 WP_277372878.1 NZ_CP120359:4565517-4565813 [Pseudomonas sp. AA-38]
MAEIVWTNPALEQLDELAHYIALDKPDAARALVRKVVEAVARLAEFPLSGRVPGELPDSVYREIVVPPCRVFYRPAEGKV
FIIHIMREERLLRAHLLE

Download         Length: 297 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9685.20 Da        Isoelectric Point: 6.7177

>AT274895 WP_277372877.1 NZ_CP120359:4565272-4565529 [Pseudomonas sp. AA-38]
MKVELVTNLKRQATKILADLHETKEPVLITEHGVPSAYLVDVDDYQFMQRRLALLDALACGERAVLEGNTLSHEQARERL
GKWLK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References