274887

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1157130..1157623 Replicon chromosome
Accession NZ_CP120352
Organism Ligilactobacillus murinus strain PG1-1-10

Toxin (Protein)


Gene name relE Uniprot ID A0A829DKF8
Locus tag P2T63_RS05830 Protein ID WP_004047837.1
Coordinates 1157348..1157623 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A829DFA4
Locus tag P2T63_RS05825 Protein ID WP_004047835.1
Coordinates 1157130..1157351 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2T63_RS05810 (P2T63_05810) 1152540..1153262 - 723 WP_179936176.1 IS30 family transposase -
P2T63_RS05815 (P2T63_05815) 1153422..1154594 - 1173 WP_004050661.1 IS256 family transposase -
P2T63_RS05820 (P2T63_05820) 1155361..1155627 + 267 WP_148458380.1 hypothetical protein -
P2T63_RS05825 (P2T63_05825) 1157130..1157351 + 222 WP_004047835.1 DUF6290 family protein Antitoxin
P2T63_RS05830 (P2T63_05830) 1157348..1157623 + 276 WP_004047837.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P2T63_RS05835 (P2T63_05835) 1157886..1158617 - 732 Protein_1097 5'-nucleotidase, lipoprotein e(P4) family -
P2T63_RS05840 (P2T63_05840) 1158818..1159111 + 294 WP_004047845.1 hypothetical protein -
P2T63_RS05845 (P2T63_05845) 1159206..1159808 + 603 WP_039936077.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
P2T63_RS05850 (P2T63_05850) 1159991..1161415 - 1425 WP_004047857.1 ATP-dependent protease ATPase subunit HslU -
P2T63_RS05855 (P2T63_05855) 1161436..1161978 - 543 WP_004047858.1 ATP-dependent protease subunit HslV -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1153422..1154594 1172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10984.72 Da        Isoelectric Point: 10.2588

>T274887 WP_004047837.1 NZ_CP120352:1157348-1157623 [Ligilactobacillus murinus]
MKEYHVEYSKRAQKQIKKLDRQIQRLLFAWIDKNLEGVSDPRIHGKGLTGNHAREWRYRIGDYRLICDIQDDIMIILALE
FGHRRSVYNKK

Download         Length: 276 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8540.55 Da        Isoelectric Point: 4.3566

>AT274887 WP_004047835.1 NZ_CP120352:1157130-1157351 [Ligilactobacillus murinus]
MATISIRLNQQEEELFKGYAELTGENLSTLFKEALKKSIDDEYDLQVYKEAYKEYQQDPVTISHADFKKELGF

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829DKF8

Antitoxin

Source ID Structure
AlphaFold DB A0A829DFA4

References