Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2101749..2101894 Replicon chromosome
Accession NZ_CP120343
Organism Salmonella enterica subsp. enterica serovar Paratyphi B strain PS_Mu_4_2021

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2101789..2101892 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2101749..2101894 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1708_RS10355 2098175..2098873 - 699 WP_021294108.1 exodeoxyribonuclease X -
P1708_RS10360 2098897..2099553 - 657 WP_021294109.1 carbon-nitrogen hydrolase family protein -
P1708_RS10365 2099661..2099891 - 231 WP_000856224.1 DNA polymerase III subunit theta -
P1708_RS10370 2100029..2100403 + 375 WP_000168393.1 CopC domain-containing protein YobA -
P1708_RS10375 2100404..2101279 + 876 WP_021294110.1 copper homeostasis membrane protein CopD -
P1708_RS10380 2101296..2101649 + 354 WP_000722368.1 YebY family protein -
- 2101749..2101894 - 146 - - Antitoxin
- 2101789..2101892 + 104 - - Toxin
P1708_RS10385 2102022..2103101 - 1080 WP_020438172.1 phage integrase Arm DNA-binding domain-containing protein -
P1708_RS10390 2103134..2104284 - 1151 Protein_2032 PD-(D/E)XK nuclease-like domain-containing protein -
P1708_RS10395 2104273..2104464 + 192 Protein_2033 glycoside hydrolase family 19 protein -
P1708_RS10400 2104518..2105051 + 534 WP_001050882.1 DUF2514 domain-containing protein -
P1708_RS10405 2105308..2105475 - 168 WP_000789530.1 lytic enzyme -
P1708_RS10410 2105540..2105728 - 189 WP_001521334.1 hypothetical protein -
P1708_RS10415 2105783..2106043 + 261 Protein_2037 DUF1441 family protein -
P1708_RS10420 2106258..2106620 + 363 Protein_2038 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2096087..2141605 45518


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T274818 NZ_CP120343:2101789-2101892 [Salmonella enterica subsp. enterica serovar Paratyphi B]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT274818 NZ_CP120343:c2101894-2101749 [Salmonella enterica subsp. enterica serovar Paratyphi B]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References