Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 123322..123998 Replicon plasmid pTiCFBP4996
Accession NZ_CP120216
Organism Agrobacterium leguminum strain CFBP4996

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CFBP4996_RS27275 Protein ID WP_080855069.1
Coordinates 123576..123998 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CFBP4996_RS27270 Protein ID WP_080855068.1
Coordinates 123322..123579 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP4996_RS27260 (CFBP4996_27260) 121612..121959 - 348 WP_080855066.1 hypothetical protein -
CFBP4996_RS27265 (CFBP4996_27265) 122392..122706 - 315 WP_080855067.1 helix-turn-helix transcriptional regulator -
CFBP4996_RS27270 (CFBP4996_27270) 123322..123579 + 258 WP_080855068.1 Arc family DNA-binding protein Antitoxin
CFBP4996_RS27275 (CFBP4996_27275) 123576..123998 + 423 WP_080855069.1 type II toxin-antitoxin system VapC family toxin Toxin
CFBP4996_RS27280 (CFBP4996_27280) 124079..124999 - 921 WP_080855070.1 LysR family transcriptional regulator -
CFBP4996_RS27285 (CFBP4996_27285) 125258..126172 + 915 WP_080855393.1 nucleotidyltransferase and HEPN domain-containing protein -
CFBP4996_RS27290 (CFBP4996_27290) 126239..126405 + 167 Protein_130 transposase -
CFBP4996_RS27295 (CFBP4996_27295) 126467..127639 - 1173 WP_080855072.1 Fic family protein -
CFBP4996_RS27300 (CFBP4996_27300) 127850..128611 - 762 WP_233283475.1 autoinducer binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..605495 605495


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15518.95 Da        Isoelectric Point: 4.9008

>T274597 WP_080855069.1 NZ_CP120216:123576-123998 [Agrobacterium leguminum]
MIVLDTNVISELWKVEPDSSVLTWIDSQMVETLYLSTITIAELRFGLATMPEGKRRTIYQDRLEREVLPVFTGRILFFDL
DASQAYAQLMARAKEAGRAIGKADGYIAAAAAVRGLIVATRDTSPFEAAGLRVINPWNVV

Download         Length: 423 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9404.69 Da        Isoelectric Point: 6.4695

>AT274597 WP_080855068.1 NZ_CP120216:123322-123579 [Agrobacterium leguminum]
MPSITIRNVPDEVHRAIRVRAAIHGRSAEAEIRSILEQAARPQGRLKLGTILTSIARDAEGLTDAEAELFNQLRDKTPAE
PMSFE

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References