Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 52702..53300 Replicon plasmid pTiCFBP4996
Accession NZ_CP120216
Organism Agrobacterium leguminum strain CFBP4996

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CFBP4996_RS26915 Protein ID WP_078053756.1
Coordinates 53007..53300 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CFBP4996_RS26910 Protein ID WP_078053757.1
Coordinates 52702..53010 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP4996_RS26880 (CFBP4996_26880) 47961..48344 + 384 WP_223565060.1 transposase -
CFBP4996_RS26885 (CFBP4996_26885) 48269..48904 + 636 WP_223565061.1 IS630 family transposase -
CFBP4996_RS26890 (CFBP4996_26890) 49412..49885 + 474 WP_078053760.1 Hsp20 family protein -
CFBP4996_RS26895 (CFBP4996_26895) 49963..50262 + 300 WP_078053759.1 DUF982 domain-containing protein -
CFBP4996_RS26900 (CFBP4996_26900) 50492..50998 - 507 WP_112967606.1 IS3 family transposase -
CFBP4996_RS26905 (CFBP4996_26905) 51661..51780 - 120 Protein_53 nitroreductase family protein -
CFBP4996_RS26910 (CFBP4996_26910) 52702..53010 + 309 WP_078053757.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CFBP4996_RS26915 (CFBP4996_26915) 53007..53300 + 294 WP_078053756.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
CFBP4996_RS26920 (CFBP4996_26920) 53572..56679 - 3108 WP_245311001.1 autotransporter outer membrane beta-barrel domain-containing protein -
CFBP4996_RS26925 (CFBP4996_26925) 57492..57734 + 243 WP_078053834.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..605495 605495
- flank IS/Tn - - 48317..48904 587


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-59)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10746.27 Da        Isoelectric Point: 5.7995

>T274595 WP_078053756.1 NZ_CP120216:53007-53300 [Agrobacterium leguminum]
VKLTWSAFALSDRDAIFTYIEADNPAAAILIDERIVSAARRLLDFPASGRLGRIAGTRELVINGTPYVAAYATTETTVRI
LRVLHGAQEWPEYLLQN

Download         Length: 294 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11084.42 Da        Isoelectric Point: 4.8892

>AT274595 WP_078053757.1 NZ_CP120216:52702-53010 [Agrobacterium leguminum]
MAANALVQTRIDAEVRDRASAVLESMGLTVSDAVRIMLTRTANEGALPLELLSGSETHDAWFRTKVLEALNDTRSDLTDD
EAEAHFAKRRAAARLKVGSTES

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References