Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 474843..475387 Replicon chromosome
Accession NZ_CP120211
Organism Agrobacterium leguminum strain CFBP4996

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CFBP4996_RS02305 Protein ID WP_162935992.1
Coordinates 475097..475387 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CFBP4996_RS02300 Protein ID WP_080852551.1
Coordinates 474843..475094 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP4996_RS02275 (CFBP4996_02275) 469923..470612 - 690 WP_003520496.1 HAD family hydrolase -
CFBP4996_RS02280 (CFBP4996_02280) 470835..471515 + 681 WP_059754101.1 GntR family transcriptional regulator -
CFBP4996_RS02285 (CFBP4996_02285) 471562..472023 + 462 WP_080853232.1 DUF1284 domain-containing protein -
CFBP4996_RS02290 (CFBP4996_02290) 471983..473083 - 1101 WP_080852552.1 hypothetical protein -
CFBP4996_RS02295 (CFBP4996_02295) 473322..474467 + 1146 WP_003520492.1 site-specific DNA-methyltransferase -
CFBP4996_RS02300 (CFBP4996_02300) 474843..475094 + 252 WP_080852551.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
CFBP4996_RS02305 (CFBP4996_02305) 475097..475387 + 291 WP_162935992.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP4996_RS02310 (CFBP4996_02310) 475425..476036 - 612 WP_080852549.1 HAD family phosphatase -
CFBP4996_RS02315 (CFBP4996_02315) 476119..477228 - 1110 WP_080852548.1 A/G-specific adenine glycosylase -
CFBP4996_RS02320 (CFBP4996_02320) 477355..477819 + 465 WP_035263001.1 hypothetical protein -
CFBP4996_RS02325 (CFBP4996_02325) 477847..478368 + 522 WP_065116149.1 DUF721 domain-containing protein -
CFBP4996_RS02330 (CFBP4996_02330) 478498..479178 + 681 WP_072494057.1 DsbA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(12-62)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11369.13 Da        Isoelectric Point: 6.4908

>T274589 WP_162935992.1 NZ_CP120211:475097-475387 [Agrobacterium leguminum]
MGFRLSLLAEEDVIRIVEEGIVLFGLAQAQKYHRELYEIFELISRNPRMARERHELLPPLRIHRFRAHLVVYAVGTDDDV
LIVRVRHAHEDWANEL

Download         Length: 291 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9413.67 Da        Isoelectric Point: 9.5892

>AT274589 WP_080852551.1 NZ_CP120211:474843-475094 [Agrobacterium leguminum]
MATMNISLPAPMKEWVEAQSRTGRYSNASDYVRDLIRKDQERGEKIAAMQRFVDEGLQSGVGYRSQEALFAEAEARSMKR
KIG

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References