274588

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 353965..354433 Replicon chromosome
Accession NZ_CP120211
Organism Agrobacterium leguminum strain CFBP4996

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag CFBP4996_RS01690 Protein ID WP_080852609.1
Coordinates 353965..354222 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A420FIF2
Locus tag CFBP4996_RS01695 Protein ID WP_059760738.1
Coordinates 354206..354433 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP4996_RS01655 (CFBP4996_01655) 348971..349600 + 630 WP_080852614.1 DNA-3-methyladenine glycosylase I -
CFBP4996_RS01660 (CFBP4996_01660) 349597..350040 + 444 WP_080852613.1 hypothetical protein -
CFBP4996_RS01665 (CFBP4996_01665) 350056..351099 - 1044 WP_121490279.1 YeiH family protein -
CFBP4996_RS01670 (CFBP4996_01670) 351181..352098 + 918 WP_080852612.1 LysR family transcriptional regulator -
CFBP4996_RS01675 (CFBP4996_01675) 352309..352683 - 375 WP_035218719.1 DUF305 domain-containing protein -
CFBP4996_RS01680 (CFBP4996_01680) 352742..353140 - 399 WP_279511025.1 hypothetical protein -
CFBP4996_RS01685 (CFBP4996_01685) 353182..353946 - 765 WP_080852610.1 hypothetical protein -
CFBP4996_RS01690 (CFBP4996_01690) 353965..354222 - 258 WP_080852609.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP4996_RS01695 (CFBP4996_01695) 354206..354433 - 228 WP_059760738.1 DUF6290 family protein Antitoxin
CFBP4996_RS01700 (CFBP4996_01700) 354590..356113 + 1524 WP_080852608.1 histidine--tRNA ligase -
CFBP4996_RS01705 (CFBP4996_01705) 356118..356486 + 369 WP_080852607.1 VOC family protein -
CFBP4996_RS01710 (CFBP4996_01710) 356503..357630 + 1128 WP_080852606.1 ATP phosphoribosyltransferase regulatory subunit -
CFBP4996_RS01715 (CFBP4996_01715) 357627..358319 + 693 WP_020812640.1 ATP phosphoribosyltransferase -
CFBP4996_RS01720 (CFBP4996_01720) 358384..358830 - 447 WP_003519535.1 DoxX family protein -
CFBP4996_RS01725 (CFBP4996_01725) 358982..359401 - 420 WP_233283518.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-85)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10226.73 Da        Isoelectric Point: 9.6874

>T274588 WP_080852609.1 NZ_CP120211:c354222-353965 [Agrobacterium leguminum]
VIWTIEYHALVQKEMRKINPETRQRIRSFLHERLAALDDPRQTGTALQDSERGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRR

Download         Length: 258 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8883.89 Da        Isoelectric Point: 4.9212

>AT274588 WP_059760738.1 NZ_CP120211:c354433-354206 [Agrobacterium leguminum]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLHLAEEATRRIQRGESKVVSAEEFWRDLDN

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A420FIF2

References